|1.||Shubina, Larisa K: 3 articles (01/2014 - 04/2012)|
|2.||Fedorov, Sergey N: 3 articles (01/2014 - 04/2012)|
|3.||Honecker, Friedemann: 3 articles (01/2014 - 04/2012)|
|4.||Dyshlovoy, Sergey A: 3 articles (01/2014 - 04/2012)|
|5.||Bokemeyer, Carsten: 3 articles (01/2014 - 04/2012)|
|6.||Proksch, Peter: 2 articles (05/2015 - 09/2014)|
|7.||Fritz, Gerhard: 2 articles (05/2015 - 09/2014)|
|8.||Jacobsen, Christine: 2 articles (01/2014 - 04/2012)|
|9.||Balabanov, Stefan: 2 articles (01/2014 - 04/2012)|
|10.||Walther, Reinhard: 2 articles (01/2014 - 04/2012)|
|1.||BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
01/01/2015 - "Significant anti-tumor effects were observed in aaptamine-administered tumor-bearing mice as compared to controls. "
01/01/2014 - "In order to explore further the mechanism of action of aaptamine and its derivatives, we studied the effects of aaptamine (1), demethyl(oxy)aaptamine (2), and isoaaptamine (3) on human cancer cell lines and on AP-1-, NF-κB-, and p53-dependent transcriptional activity in murine JB6 Cl41 cells. "
03/25/2004 - "The marine sponge constituent aaptamine (1) has been converted to the cancer cell growth inhibitor and antibiotic designated hystatin 2 (8a). "
03/01/2004 - "By use of bioassay (murine P388 lymphocytic leukemia cell line) guided isolation procedures, extracts of the Republic of Singapore marine sponge Hymeniacidon sp. were found to contain demethyloxyaaptamine (1) and aaptamine (3) as prominent cancer cell growth inhibitory constituents accompanied by the trace, albeit more active, component isoaaptamine (4). "
|3.||Germ Cell and Embryonal Neoplasms (Germ Cell Tumor)
04/06/2012 - "Proteomic profiling of germ cell cancer cells treated with aaptamine, a marine alkaloid with antiproliferative activity."
01/01/2014 - "Earlier, we have found that aaptamine and its derivatives demonstrate equal anticancer effects against the human germ cell cancer cell lines NT2 and NT2-R and cause some changes in the proteome of these cells. "
01/16/2014 - "Activity of aaptamine and two derivatives, demethyloxyaaptamine and isoaaptamine, in cisplatin-resistant germ cell cancer."
|4.||Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
|5.||Osteosarcoma (Osteogenic Sarcoma)
|7.||1,4- bis(benzyl)- 8,9- dimethoxy- 4H- benzo(de)(1,6)naphthyridin- 1- ium
|1.||Heterologous Transplantation (Xenotransplantation)