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1-oxiranylpyrene
RN & structure given in first source; RN not in Chemline 1/85
Networked:
1
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Hydrocarbons: 1713
Cyclic Hydrocarbons: 97
Aromatic Hydrocarbons: 291
Polycyclic Aromatic Hydrocarbons: 2020
Pyrenes: 10
1-oxiranylpyrene: 1
Polycyclic Compounds: 6
Polycyclic Aromatic Hydrocarbons: 2020
Pyrenes: 10
1-oxiranylpyrene: 1
Related Diseases
1.
Carcinogenesis
11/06/1984 - "
Reaction of 1-oxiranylpyrene (1-OP) with DNA and the structures of the covalent and noncovalent complexes formed were studied in aqueous media (5 mM phosphate buffer with 0.1 M NaCl, pH 7) by utilizing the techniques of absorption, fluorescence and linear dichroism spectroscopy in order to gain an understanding of possible structure-activity relationships for polycyclic aromatic hydrocarbon epoxides in tumorigenesis and carcinogenesis, and the results were compared with those obtained for the highly active benzo[a]pyrene diol epoxide (BaPDE).
"
Related Drugs and Biologics
1.
Polycyclic Aromatic Hydrocarbons (Polynuclear Aromatic Hydrocarbons)
2.
Phosphates (Orthophosphate)
3.
Epoxy Compounds (Epoxides)
4.
DNA (Deoxyribonucleic Acid)
5.
Buffers
6.
Benzo(a)pyrene