O-(alpha-idopyranosyluronic acid)-(1-3)-2,5-anhydroalditol-4-sulfate

iduronidase substrate; tritium-labeled cpd used in diagnosis of mucopolysaccharidosis 1; structure given in first source; RN given not in Chemline 12/86

Also Known As:

IdoA-anT4S; D-Altritol, 2,5-anhydro-4-O-alpha-L-idopyranuronosyl-, (2S-(2alpha,5alpha,6beta(S*)))-

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Carbohydrates: 22023
- Polysaccharides: 15383
  - Oligosaccharides: 3566
    - Disaccharides: 990
      - O-(alpha-idopyranosyluronic acid)-(1-3)-2,5-anhydroalditol-4-sulfate: 1
- Sugars: 11126
  - Disaccharides: 990
    - O-(alpha-idopyranosyluronic acid)-(1-3)-2,5-anhydroalditol-4-sulfate: 1

Related Diseases

1.	Mucopolysaccharidosis II (Hunter Syndrome) 10/28/1983 - "IdoA2S-anT4S was degraded to IdoA-anT4S and then to anT4S by normal-fibroblast homogenates, whereas fibroblasts from alpha-L-iduronidase-deficient and sulfoiduronate sulfatase-deficient (Mucopolysaccharidosis Type II) patients produced considerably decreased levels of anT4s and IdoA-anT4S (and anT4S), respectively."
2.	Mucopolysaccharidosis I (Hurler Syndrome) 10/28/1983 - "Activity toward IdoA-anT4S was not observed with fibroblast homogenates from alpha-L-iduronidase-deficient patients (Mucopolysaccharidosis Type I). "

Related Drugs and Biologics

1.	Iduronidase (alpha-L-Iduronidase)
2.	Iduronate Sulfatase