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alpha- amino- (4- hydroxybenzylidene)diphosphonate
Also Known As:
BDP3; Phosphonic acid, (amino(4-hydroxyphenyl)methylene)bis-, (8S-cis)-
Networked:
4
relevant articles (
1
outcomes,
0
trials/studies)
Relationship Network
Bio-Agent Context: Research Results
Organic Chemicals: 133
Hydrocarbons: 1713
Cyclic Hydrocarbons: 97
Aromatic Hydrocarbons: 291
Benzene Derivatives: 17
Benzylidene Compounds: 10
alpha-amino-(4-hydroxybenzylidene)diphosphonate: 4
Organophosphorus Compounds: 300
Organophosphonates: 424
Diphosphonates: 11565
alpha-amino-(4-hydroxybenzylidene)diphosphonate: 4
Related Diseases
1.
Neoplasms (Cancer)
01/01/2023 - "
Such NO-induced fluorescence signals of BDP3 are validated to correlate well with the phenotypes of TAMs detected in macrophage cell lines and tumor tissues.
"
01/01/2023 - "
By virtue of good biocompatibility and appropriate tumor retention time, BDP3 could be a potential fluorescent probe for noninvasive evaluation of the immunotherapeutic efficacy of macrophage-targeted immunotherapy in living animals.
"
2.
Neoplasm Metastasis (Metastasis)
01/01/1986 - "
The bone metastasis/bone marrow dose ratio by comparison with 131I labeled BDP3 is, however, almost equal.
"
01/01/1986 - "
Theoretical replacement of 131I in iodinated BDP3 with radioisotopes emitting higher energy electrons yielded best bone metastasis/organ ratios for 32P labeled BDP3.
"
12/01/1984 - "
Iodine-131-labeled diphosphonates for the palliative treatment of bone metastases: I. Organ distribution and kinetics of I-131 BDP3 in rats.
"
12/01/1984 - "
LD50 measurements in rats amounted to 64 mg/kg. Because of these biokinetical characteristics and the simple labeling procedure, I-131 BDP3 is suggested as a radiopharmaceutical for the palliative treatment of pain that often accompanies disseminated bone metastases.
"
08/01/1986 - "
The kinetics, dosimetry, and response of iodine-131 alpha-amino-(4-hydroxybenzylidene)-diphosphonate ([131I]BDP3) treatment were investigated with patients who had pain symptoms from bone metastases of various primary carcinoma.
"
3.
Pain (Aches)
12/01/1984 - "
LD50 measurements in rats amounted to 64 mg/kg. Because of these biokinetical characteristics and the simple labeling procedure, I-131 BDP3 is suggested as a radiopharmaceutical for the palliative treatment of pain that often accompanies disseminated bone metastases.
"
08/01/1986 - "
The kinetics, dosimetry, and response of iodine-131 alpha-amino-(4-hydroxybenzylidene)-diphosphonate ([131I]BDP3) treatment were investigated with patients who had pain symptoms from bone metastases of various primary carcinoma.
"
4.
Carcinoma (Carcinomatosis)
08/01/1986 - "
The kinetics, dosimetry, and response of iodine-131 alpha-amino-(4-hydroxybenzylidene)-diphosphonate ([131I]BDP3) treatment were investigated with patients who had pain symptoms from bone metastases of various primary carcinoma.
"
Related Drugs and Biologics
1.
Fluorescent Dyes (Fluorescent Probes)
2.
Diphosphonates (Bisphosphonates)
3.
Radiopharmaceuticals
4.
Radioisotopes (Radionuclides)
5.
Iodine-131
Related Therapies and Procedures
1.
Immunotherapy
2.
Palliative Care (Palliative Therapy)