chrysin

09/01/2021 - "The findings indicate that chrysin has protective effects against neurological conditions by modulating oxidative stress, inflammation, and apoptosis in animal models. "
01/01/2019 - "The findings indicate that chrysin has protective effects against diabetes outcomes by modulating oxidative stress, inflammation, and apoptosis in animal models. "
01/01/2019 - "Previous studies reported that nuclear factor κB (NF-κB) is important in the inflammatory response in endothelial cells, particularly in regulating adhesion molecules, and our data shed light on the mechanisms whereby chrysin suppressed endothelial inflammation via the NF-κB signaling pathway. "
01/01/2022 - "It was also found that chrysin inhibited the inflammation and oxidative stress in mice with D-gal induction. "
01/01/2022 - "Taken together, the mechanisms in which chrysin protects against cardiometabolic disorder are more than merely antioxidation and anti-inflammation in the cardiovascular system."

09/01/2016 - "The in vivo antitumor efficacy of chrysin on transplanted CT26 tumor cells in BALB/c mice was investigated. "
01/01/2023 - "Studies have suggested that chrysin can enhance the sensitivity of tumor cells to apoptosis. "
01/01/2022 - "In this study, we investigated the effects of chrysin on tumor progression in hypoxic PC-3 cells. "
01/01/2021 - "Conclusion: This study concludes that chrysin can be used as a potential epigenetic modifier for cancer treatment and warrants for further experimental validation."
01/01/2021 - "This study suggests that chrysin exhibited anti-tumor effects through a H19/let-7a/COPB2 axis."

01/01/2023 - "Possible mechanisms involved in the protective effects of chrysin against lead-induced cognitive decline: An in vivo study in a rat model."
01/01/2023 - "However, chrysin treatment improved cognitive dysfunction, ameliorated hippocampal LTP impairment, modulated inflammatory status, reduced Pb concentration, and prevented neuronal loss in the Pb-exposed rats. "
01/01/2023 - "The present study was designed to examine the putative effects of chrysin against Pb-induced cognitive impairment and the possible involved mechanisms. "
01/01/2020 - "This study demonstrates that chrysin may have beneficial effects in the treatment of cognitive impairment and help recover the brain dysfunction induced by I/R."
12/01/2021 - "Here, we evaluated the effect of chrysin on cognitive impairment in hypothyroid female mice by exploring neuroplasticity. "

09/23/2021 - "This study investigated the nephroprotective role of chrysin in the prevention of CsA-induced renal fibrosis and elucidated a mechanism of inhibition against CsA-induced EMT in proximal tubule cells. "
12/01/2018 - "This study was designed to investigate the effect and mechanism of chrysin on myocardial fibrosis. "
07/09/2018 - "The in vivo study explored the demoting effects of 10 mg/kg chrysin on glomerular fibrosis in a type 2 diabetic model. "
10/05/2015 - "Histopathological investigations showed that hepatic fibrosis grade was markedly reduced in the chrysin groups compared to the fibrotic one. "
07/01/2015 - "• Chrysin inhibits tubular EMT-mediated tubulointerstitial fibrosis in mouse kidneys. "

01/01/2019 - "This present study demonstrates that chrysin exerts an anti-neuroinflammatory effect via a novel mechanism, the upregulation of A20 expression, also validates A20 is a novel effective pharmacological target for developing agents in the treatment of neuroinflammation-related diseases."
02/10/2023 - "Furthermore, downregulation of TREM2 blocked the anti-neuroinflammation of Chrysin, and inhibited the shift of M1 phenotype to M2 phenotype. "
02/01/2019 - "Also the effect of chrysin on motor impairment, cognitive deficits, oxidative stress, neuroinflammation, apoptosis and histopathological damage was assessed. "
04/01/2017 - "This data suggests that chrysin effectively acts as a therapeutic agent to treat hyperammonemia mediated neuroinflammation."
11/26/2010 - "These results suggest that chrysin may act as a potential therapeutic agent for various neurodegenerative diseases involving neuroinflammation."