alpha- (4- pyridyl- 1- oxide)- N- tert- butylnitrone

10/01/2002 - "Ischemia-reperfusion increased 4-POBN/radical adducts in bile nearly twofold, an effect largely blocked by GTE. "
01/01/1993 - "Cup fluid was subsequently replaced every 15 min during ischemia and every 10 min during reperfusion with fresh POBN containing CSF and the collected cortical superfusates were analyzed for radical adducts by EPR spectroscopy. "
01/01/1993 - "Prior to the onset of sample collection, both cups were perfused with artificial cerebrospinal fluid (aCSF) containing the spin trap agent alpha-(4-pyridyl-1-oxide)-N-tert butylnitrone (POBN 100 mM) for 20 min. In addition 50 mg/kg BW of POBN was administered intraperitoneally (IP) 20 min prior to ischemia in order to improve our ability to detect free radical adducts. "
08/01/1991 - "Global hepatic ischemia was induced in 19 rats in four groups: saline solution, phenyl-N-tert-butyl nitrone (PBN), alpha 1-pyridyl-N-oxide N-tert-butyl nitrone (POBN), and 5,5-dimethyl-1-pyrroline-N-oxide (DMPO). "
10/01/1994 - "Amflutizole also eliminated the ischemia/reperfusion-evoked generation of free radical adducts of alpha-(4-pyridyl-1-oxide)-N-tert-butylnitrone (POBN) detected by electron spin resonance. "

12/01/1998 - "These studies, therefore, provide additional evidence that acute Cr(VI) poisoning is associated with enhanced generation of F2-isoprostanes in vivo and tentatively identify the radical species that is produced as the POBN-pentyl radical adduct."

10/29/2004 - "In this study, rat pheochromocytoma (PC12) cells were exposed to Abeta25-35 and confirmed free radical generations using two kinds of spin trap agents, 5,5-dimethyl-1-pyrroline-N-oxide; DMPO and alpha-(4-pyridyl-1-oxide)-N-tert-butylnitrone; POBN. "

07/21/2000 - "In contrast, studies with the K562 human erythroleukemia cell line, which is often used for comparison with the HL-60, and with high passaged HL-60 cells (spent HL-60) studied under the same conditions failed to generate POBN(.). "

12/01/2016 - "However, postoperative bulla neogenesis (POBN) along the staple line is relatively common and promotes PSP recurrence. "
10/01/2015 - "However, postoperative bulla neogenesis (POBN) along the staple line is not rare and is a factor promoting PSP recurrence. "