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2'-guanidyl-2'-deaminogentamicin C1

Also Known As:

S 86451; S-86451; S86451

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Carbohydrates: 22023
- Glycosides: 2119
  - Aminoglycosides: 5131
    - Gentamicins: 7307
      - 2'-guanidyl-2'-deaminogentamicin C1: 1

Related Diseases

1.

01/01/1984 - "The nephrotoxic potential of S86451 (2'guanidyl, 2'deamino gentamicin C1) has been investigated in Sprague-Dawley rats at 10 and 25 mg/kg, in comparison with gentamicin at 4 and 10 mg/kg. The criteria were (i) the severity of the lysosomal phospholipidosis, as assessed by both biochemical and morphological investigations; (ii) the degree of tubular regeneration, a consequence of the aminoglycoside-induced focal necrosis measured by 3H-thymidine incorporation into kidney cortex DNA. "

Related Drugs and Biologics

1.	Gentamicins (Gentamicin)
2.	DNA (Deoxyribonucleic Acid)
3.	Dihydrotachysterol (AT 10)
4.	Aminoglycosides
5.	gentamicin C