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2'-guanidyl-2'-deaminogentamicin C1
Also Known As:
S 86451; S-86451; S86451
Networked:
1
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Carbohydrates: 22023
Glycosides: 2119
Aminoglycosides: 5131
Gentamicins: 7307
2'-guanidyl-2'-deaminogentamicin C1: 1
Related Diseases
1.
Necrosis
01/01/1984 - "
The nephrotoxic potential of S86451 (2'guanidyl, 2'deamino gentamicin C1) has been investigated in Sprague-Dawley rats at 10 and 25 mg/kg, in comparison with gentamicin at 4 and 10 mg/kg. The criteria were (i) the severity of the lysosomal phospholipidosis, as assessed by both biochemical and morphological investigations; (ii) the degree of tubular regeneration, a consequence of the aminoglycoside-induced focal necrosis measured by 3H-thymidine incorporation into kidney cortex DNA.
"
Related Drugs and Biologics
1.
Gentamicins (Gentamicin)
2.
DNA (Deoxyribonucleic Acid)
3.
Dihydrotachysterol (AT 10)
4.
Aminoglycosides
5.
gentamicin C