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3-acetyldeoxynivalenol

Also Known As:

3-ADON; acetylDON

Networked: 11 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Terpenes: 1461
    - Sesquiterpenes: 1370
      - Trichothecenes: 97
        3-acetyldeoxynivalenol: 11
Polycyclic Compounds: 6
- Macrocyclic Compounds: 15
  - Trichothecenes: 97
    - 3-acetyldeoxynivalenol: 11
Biological Factors: 2472
- Biological Toxins: 20
  - Mycotoxins: 1745
    - Trichothecenes: 97
      - 3-acetyldeoxynivalenol: 11

Experts

1.	Pestka, James J: 3 articles (08/2016 - 01/2013)
2.	Wu, Wenda: 3 articles (08/2016 - 01/2013)
3.	Sugita-Konishi, Yoshiko: 2 articles (04/2014 - 01/2013)
4.	Watanabe, Maiko: 2 articles (04/2014 - 01/2013)
5.	Zhang, Haibin: 2 articles (04/2014 - 01/2013)
6.	Bursian, Steven: 1 article (08/2016)
7.	Male, Denis: 1 article (08/2016)
8.	Mitchell, Nicole J: 1 article (08/2016)
9.	Wu, Felicia: 1 article (08/2016)
10.	Chen, Bo: 1 article (12/2014)

Related Diseases

1.	Body Weight (Weight, Body) 07/01/1985 - "Mice were killed 2, 4, 6, 12, 24, 48 and 96 hours after intragastrical administration of 0, 5, 10, 20, or 40 mg/kg body weight of 3-acetyldeoxynivalenol. " 07/01/1985 - "3-Acetyldeoxynivalenol caused a dose-related depressed feed consumption within the first seven days and reduced body weight until day 14 when fed at levels up to 10 ppm. When fed at a level of 20 ppm, an initial depression in body weight gain and a general malaise were followed by a return to normal. " 12/01/2014 - "However, if the cumulative health risks were calculated based on the combined consideration of DON with either 3-ADON or 15-ADON or both, the DI values in 95th percentile were up to 1087 ng/kg body weight/day, exceeding the Provisional Maximum Tolerable Daily Intake (PMTDI) of 1000 ng/kg body weight/day and hence representing potential health risks to the population in Shanghai. "
2.	Fusariosis 09/01/1986 - "Deoxynivalenol and 3-acetyldeoxynivalenol - mycotoxins associated with wheat head fusariosis in Poland." 03/01/1987 - "In handly selected kermels of cobs with symptoms of red fusariosis /red ear rot/ which stated only about 5% of infected cobs, were present: zearalenone up 20 mg/kg, deoxynivalenol /vomitoxin/ up 170 mg/kg and 3-acetyldeoxynivalenol up 40 mg/kg. In axial stems the amount of mycotoxins was 1.5-8 times higer than in kernels."
3.	Vomiting 01/01/2013 - "To address this, we compared potencies of DON, 15-acetyldeoxynivalenol (15-ADON), 3-acetyldeoxynivalenol (3-ADON), fusarenon X (FX), and nivalenol (NIV) in the mink emesis model following intraperitoneal (ip) and oral administration. " 08/01/2016 - "We used a mink emesis model to compare the toxicities of deoxynivalenol, 3-acetyldeoxynivalenol, 15-acetyldeoxynivalenol, nivalenol, fusarenon-X, HT-2 toxin, and T-2 toxin. "
4.	Chromosome Aberrations (Chromosome Abnormalities) 01/01/1988 - "Pure toxins of NIV, DON, T-2, and 3-ADON also induced chromosome aberrations in V79 cells at very low concentrations (ng levels/ml medium). " 01/01/1988 - "Pure toxins of NIV, DON, T-2 and 3-ADON could induce chromosome aberrations in V79 cells starting from 1 ng/ml-a very low concentration. "
5.	Carcinoma (Carcinomatosis) 02/15/2013 - "In human lung carcinoma A549 cells, deoxynivalenol and 3-acetyldeoxynivalenol inhibited the expression of intercellular adhesion molecule-1 (ICAM-1) induced by TNF-α more strongly than that induced by interleukin 1α (IL-1α), whereas T-2 toxin and verrucarin A exerted nonselective inhibitory effects. "

Related Drugs and Biologics

1.	deoxynivalenol
2.	15-acetyldeoxynivalenol
3.	nivalenol
4.	fusarenon-X
5.	T-2 Toxin (T 2 Toxin)
6.	Mycotoxins
7.	Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)
8.	Zearalenone
9.	Interleukins
10.	Cholecystokinin (Pancreozymin)

Related Therapies and Procedures

1.	Oral Administration