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4-desmethoxyverapamil

Also Known As:

(-)-H3-desmethoxyverapamil; 4-DMV; D 888; D-888; D888; Benzeneacetonitrile, 3,4-dimethoxy-alpha-(3-((2-(3-methoxyphenyl)ethyl)methylamino)propyl)-alpha-(1-methylethyl)-, (-)-

Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amines: 4871
  - Ethylamines: 5
    - Phenethylamines: 28
      - Verapamil: 6163
        4-desmethoxyverapamil: 2

Related Diseases

1.	Nervous System Diseases (Neurological Disorders) 05/21/1993 - "In the present study, DHP/[3H]PN200-110 and PA/[3H](-)-D-888 binding parameters were determined in various brain areas obtained at autopsy from Alzheimer's (AD), Parkinson's (PD), Huntington's (HD) disease patients, and healthy age-matched controls as a means to assess the integrity of L-type channels in these neurological disorders often associated with the aging brain. "
2.	Hypertrophy 08/01/1989 - "For (-)[3H]D888 binding, the Kd values changed with age, but there was no hypertension or hypertrophy-linked increase in Bmax. "
3.	Hypertension (High Blood Pressure) 08/01/1989 - "For (-)[3H]D888 binding, the Kd values changed with age, but there was no hypertension or hypertrophy-linked increase in Bmax. "