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deoxyharringtonine
RN given refers to 3(R)-isomer
Also Known As:
deoxyharringtonine, (3(S))-isomer
Networked:
4
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
Alkaloids: 5398
Harringtonines: 5
deoxyharringtonine: 4
Fused-Ring Heterocyclic Compounds
2-Ring Heterocyclic Compounds
Benzazepines: 5
Harringtonines: 5
deoxyharringtonine: 4
4 or More Rings Heterocyclic Compounds
Harringtonines: 5
deoxyharringtonine: 4
Experts
1.
Eckelbarger, Joseph D
: 1 article (08/2006)
2.
Gin, David Y
: 1 article (08/2006)
3.
Wilmot, Jeremy T
: 1 article (08/2006)
Related Diseases
1.
Leukemia
09/01/1984 - "
Semisynthetic deoxyharringtonine for treating leukemia in mice and humans.
"
09/01/1984 - "
The effects of two varieties of semisynthetic deoxyharringtonine on the tumor mass and survival time of mice with murine leukemia were evaluated.
"
08/16/2006 - "
Deoxyharringtonine (1) is among the most potent of the anti-leukemia alkaloids isolated from the Cephalotaxus genus.
"
08/16/2006 - "
Total synthesis of the anti-leukemia alkaloid (-)-deoxyharringtonine.
"
01/01/1992 - "
Harringtonine, homoharringtonine, deoxyharringtonine and isoharringtonine isolated from Cephalotaxus plant are the esters of cephalotaxine with significant inhibitory activity against P-388 leukemia.
"
2.
Neoplasms (Cancer)
09/01/1984 - "
The effects of two varieties of semisynthetic deoxyharringtonine on the tumor mass and survival time of mice with murine leukemia were evaluated.
"
3.
Lymphoid Leukemia
01/01/1975 - "
The new "rearranged" deoxyharringtonine isomer 2b proved to be inactive in the P-388 lymphocytic leukemia system and thus further delineated the structural requirements for antitumor activity in this series of alkaloids.
"
Related Drugs and Biologics
1.
Alkaloids
2.
Esters
3.
Homoharringtonine
4.
harringtonin
5.
isoharringtonine