ORF 13811

structure given in first source; RN given refers to Ca[2:1]salt

Also Known As:

4-(5-hydroxy-4,8-dimethyl-7-nonenyl)-4-methyl-3,8-dioxabicyclo(3.2.1)octane-1-acetic acid; ORF 13811, L-arginine (1:1) salt; ORF 13811, L-lysine (1:1) salt; ORF-13811

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Terpenes: 1461
    - Diterpenes: 1470
      - ORF 13811: 1

Related Diseases

Uterine Hemorrhage (Uterine Bleeding)

07/01/1984 - "The single oral ED50 for contragestational activity in the pregnant guinea pig (day 22), mouse (day 16) and rat (day 16) is in the range of 6 to 10 mg/kg. In pregnant beagle dogs, a dose-related contragestational effect was obtained within several days after oral administration of ORF 13811 in the dosage range of 10 to 30 mg/kg. ORF 13811, when administered to pregnant baboons, caused dose-related vaginal bleeding and evacuation of uterine contents within 3 days following treatment with oral doses of 40 to 60 mg/kg. Serum progesterone levels were decreased in baboons and the degree of reduction correlated with contragestational activity. "

Related Drugs and Biologics

1.	Progesterone

Related Therapies and Procedures

1.	Oral Administration