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4-hydroxyisophthalic acid

structure given in first source

Also Known As:

4-HIPA; 4-hydroxy-iso-phthalate; 4-hydroxy-isophthalate

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Carboxylic Acids: 973
  - Carbocyclic Acids
    - Phthalic Acids: 1
      - 4-hydroxyisophthalic acid: 3

Experts

1.	Shivanandappa, T: 2 articles (07/2020 - 11/2016)
2.	AlYahya, Sami: 1 article (01/2021)
3.	Alghamdi, Saad: 1 article (01/2021)
4.	Alomary, Mohammad N: 1 article (01/2021)
5.	Anand, Santosh: 1 article (01/2021)
6.	Ansari, Mohammad Azam: 1 article (01/2021)
7.	Dundaiah, Bhagyalakshmi: 1 article (01/2021)
8.	Lakshmeesha, Thimappa Ramachandrappa: 1 article (01/2021)
9.	Madhugiri Gopinath, Mamatha: 1 article (01/2021)
10.	Punekar, Shital Manohar: 1 article (01/2021)

Related Diseases

1.	Neurodegenerative Diseases (Neurodegenerative Disease) 01/01/2021 - "4-Hydroxyisophthalic acid (4-HIA) is a bioactive compound present in the roots of Decalepis hamiltonii, which has attracted considerable attention in attenuating oxidative stress-related neurodegenerative diseases. " 11/01/2016 - "Our findings showed that 4-HIPA can be considered as a suitable therapeutic candidate for drug development towards treatment of neurodegenerative disorders."
2.	Neoplasms (Cancer) 07/01/2020 - "Natural bioactive 4-Hydroxyisophthalic acid (4-HIPA) exhibited antiproliferative potential by upregulating apoptotic markers in in vitro and in vivo cancer models."
3.	Breast Neoplasms (Breast Cancer) 07/01/2020 - "Results of the long-term colony formation and scratch assay further reaffirmed that 4-HIPA inhibited the growth and proliferation in breast cancer cells. " 07/01/2020 - "4-HIPA was screened in vitro against human breast cancer cell lines MCF-7, MDA-MB-468 and normal human breast epithelial cell MCF-10, and demonstrated that human breast cancer cell lines, in contrast to MCF-10, are sensitive to 4-HIPA .4-HIPA showed marked reduction in cell viability and short-term proliferation assays in these cells. "