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3'-deamino-3'-hydroxydoxorubicin

substitution of the basic amino group at the C-3' of doxorubicin by a hydroxyl group overcomes recognition of the multidrug resistant P-glycoprotein and limits cardiotoxicity; structure given in first source
Also Known As:
3'-deamino-4'-epi-3'-hydroxydoxorubin; 3-DHD; hydroxyrubicin; 5,12-Naphthacenedione, 10-((2,6-dideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-, (8S-cis)-
Networked: 1 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Related Diseases

1. Leukemia P388

Related Drugs and Biologics

1. Doxorubicin (Adriamycin)