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fluorescein-ovalbumin

application to conjunctival sac causes sensitization for conjunctival type 1 hypersensitivity reactions & mast cell degranulation

Also Known As:

fluoresceinyl ovalbumin

Networked: 5 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Yamaki, Kouya: 1 article (01/2016)
2.	Yoshino, Shin: 1 article (01/2016)
3.	Khatami, Mahin: 1 article (03/2005)

Related Diseases

1.	Inflammation (Inflammations) 03/01/2005 - "In a series of studies conducted in the 1980s and 1990s, an experimental model of acute and chronic inflammation was established in guinea pig conjunctiva by topical application of fluoresceinyl ovalbumin (FLOA) for up to 30 months. "
2.	Immediate Hypersensitivity 01/01/1985 - "Type-I hypersensitivity reactions were induced in guinea pigs by repeated topical/conjunctival application of fluoresceinyl ovalbumin (FL-OA). " 01/01/1985 - "Induction and down-regulation of conjunctival type-I hypersensitivity reactions in guinea pigs sensitized topically with fluoresceinyl ovalbumin."
3.	Hypersensitivity (Allergy) 11/01/1984 - "Repeated topical applications of fluoresceinyl ovalbumin (FL-OA) to the conjunctival sac of guinea pigs sensitized them for conjunctival type 1 hypersensitivity reactions and mast cell degranulation. "
4.	Hyperplasia 09/01/1988 - "Long-term (greater than 2 years) topical, conjunctival application of fluoresceinyl ovalbumin (FL-OA) induced allergic conjunctivitis-like lesions and hyperplasia of conjunctival-associated lymphoid tissue (CALT) in guinea pigs. "
5.	Allergic Conjunctivitis (Giant Papillary Conjunctivitis) 09/01/1988 - "Long-term (greater than 2 years) topical, conjunctival application of fluoresceinyl ovalbumin (FL-OA) induced allergic conjunctivitis-like lesions and hyperplasia of conjunctival-associated lymphoid tissue (CALT) in guinea pigs. "

Related Drugs and Biologics

1.	Fluorescein-5-isothiocyanate (FITC)
2.	Immunoglobulin E (IgE)
3.	Antigen-Antibody Complex (Immune Complex)

Related Therapies and Procedures

1.	Intravenous Injections