musk tibetine (musk tibetene)

in contrast to other musk cpds this cpd does not cause allergic photocontact dermatitis; structure given in first source

Also Known As:

musk tibetene; 2,6-dinitro-3,4,5-trimethyl-tert-butylbenzene

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Benzene Derivatives: 17
        Nitrobenzenes: 7
        Dinitrobenzenes: 187
        musk tibetine: 4
- Nitro Compounds: 66
  - Nitrobenzenes: 7
    - Dinitrobenzenes: 187
      - musk tibetine: 4

Related Diseases

1.	Phototoxic Dermatitis (Phototoxicity) 02/01/1986 - "Musk tibetene and musk moskene were negative for phototoxicity, photoallergenicity and contact sensitivity under the test conditions. " 02/01/1986 - "The potential of 4 related nitro musk substances (musk tibetene, musk ketone, musk xylol, and musk moskene) to cause photoallergy, phototoxicity, and/or contact sensitivity was compared to that of musk ambrette, a known photoallergen. "
2.	Photoallergic Dermatitis (Photoallergy) 02/01/1986 - "The potential of 4 related nitro musk substances (musk tibetene, musk ketone, musk xylol, and musk moskene) to cause photoallergy, phototoxicity, and/or contact sensitivity was compared to that of musk ambrette, a known photoallergen. "
3.	Hypersensitivity (Allergy) 10/01/1985 - "A patient with photocontact allergy to musk ambrette was investigated with patch and photopatch testing with dilutions of musk ambrette and 4 other nitro-musk compounds (musk ketone, moskene, musk tibetine, musk xylene) as well as with in vitro ultraviolet-irradiated solutions of musk ambrette. "
4.	Hepatocellular Carcinoma (Hepatoma) 03/14/1997 - "Musk xylene, musk ketone, musk ambrette, musk moskene and musk tibetene revealed no genotoxicity in the micronucleus test with human lymphocytes and with the human hepatoma cell line Hep G2." 03/14/1997 - "The nitro musk compounds musk xylene (1-tert.-butyl-3,5-dimethyl-2,4,6-trinitrobenzene), musk ketone (4-tert.-butyl-3,5-dinitro-2,6-dimethylacetophenone), musk ambrette (1-tert.-butyl-4-methyl-6-methoxy-3,5-dinitrobenzene), musk moskene (1,1,3,3,5-pentamethyl-4,6-dinitroindane) and musk tibetene (1-tert.-butyl-3,4,5-trimethyl-2,6-dinitrobenzene) were tested for their genotoxic activity in the micronucleus test (MN) with human lymphocytes in vitro and the human hepatoma cell line Hep G2. "
5.	Contact Dermatitis (Eczema, Contact) 02/01/1986 - "Musk tibetene and musk moskene were negative for phototoxicity, photoallergenicity and contact sensitivity under the test conditions. " 02/01/1986 - "The potential of 4 related nitro musk substances (musk tibetene, musk ketone, musk xylol, and musk moskene) to cause photoallergy, phototoxicity, and/or contact sensitivity was compared to that of musk ambrette, a known photoallergen. "

Related Drugs and Biologics

1.	moskene
2.	musk ketone
3.	musk xylene
4.	musk ambrette (artificial)
5.	musk