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N-acetylmuramyl-alanylglutamine methyl ester
RN given refers to (D)-isomer
Also Known As:
N-acetylmuramyl-alanylglutamine methyl ester, (D-alpha)-isomer; murametide
Networked:
4
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Carbohydrates: 22023
Amino Sugars: 110
Muramic Acids: 28
Acetylmuramyl-Alanyl-Isoglutamine: 467
N-acetylmuramyl-alanylglutamine methyl ester: 4
Sugar Acids: 4
Muramic Acids: 28
Acetylmuramyl-Alanyl-Isoglutamine: 467
N-acetylmuramyl-alanylglutamine methyl ester: 4
Amino Acids, Peptides, and Proteins: 1
Peptides: 82426
Glycopeptides: 1928
Acetylmuramyl-Alanyl-Isoglutamine: 467
N-acetylmuramyl-alanylglutamine methyl ester: 4
Related Diseases
1.
Fever (Fevers)
01/01/1989 - "
Murametide given 30 min before rIL-1 beta, blocked the expected IL-1-induced fevers but not the rIL-1 beta-mediated increases of slow-wave sleep and decreases of rapid-eye-movements sleep.
"
01/01/1989 - "
Therefore, the effects of murametide on IL-1-induced sleep and fever responses were determined.
"
09/01/1984 - "
Moreover, plasma from rabbits treated with murametide transferred into untreated recipients elicited a febrile response typical of EP fever and comparable with that induced by plasma from MDP-treated animals.
"
04/01/1986 - "
Murametide, which has been previously shown to induce secretion of circulating EP but prevents in vivo fever response, was unable to prevent an EP-induced effect on plasma metal concentrations.
"
09/01/1984 - "
Moreover, pretreatment of rabbits with murametide decreased fever responses induced by certain high-molecular-weight exogenous pyrogens as mediated through the production of EP.
"
2.
Infections
01/01/1989 - "
A significant proportion of MDP or Murametide-treated animals, in contrast to controls, survived the MHV-3 infection.
"
01/01/1989 - "
MDP and a nonpyrogenic analog, Murametide, inhibited the steep elevation of serum transaminases induced by MHV-3 irrespective of whether the immunomodulators were administered before or after the infection.
"
Related Drugs and Biologics
1.
Pyrogens
2.
Metals
3.
Interleukin-1 (Interleukin 1)
4.
Immunologic Factors (Immunomodulators)
5.
Esters
6.
Transaminases (Aminotransferases)