|1.||Chitty, Lyn S: 6 articles (10/2015 - 01/2014)|
|2.||Wang, Wei: 5 articles (09/2015 - 06/2013)|
|3.||Chen, Fang: 4 articles (11/2015 - 06/2013)|
|4.||Bianchi, Diana W: 4 articles (10/2015 - 01/2014)|
|5.||Benn, Peter: 4 articles (10/2015 - 01/2014)|
|6.||Wilkins-Haug, Louise: 4 articles (07/2015 - 01/2014)|
|7.||Cram, David S: 4 articles (04/2015 - 01/2015)|
|8.||Zhang, Jianguang: 4 articles (04/2015 - 06/2014)|
|9.||Jiang, Hui: 3 articles (11/2015 - 08/2014)|
|10.||Abuhamad, Alfred Z: 3 articles (10/2015 - 12/2014)|
|1.||Down Syndrome (Down's Syndrome)
04/01/2014 - "Prenatal testing for Down syndrome through the use of non-invasive prenatal testing (NIPT) has been increasingly implemented in clinical practice and a recent cost analysis suggests that NIPT is cost effective when compared to other screening modalities in high risk populations. "
03/24/2015 - "NIPT may be used to reduce unnecessary invasive prenatal diagnosis by improving the efficacy of current mid-trimester screening strategy, particularly for trisomy 21."
10/01/2015 - "A cross-sectional questionnaire study across nine maternity units and three conferences in the UK designed to assess opinions regarding test delivery and how information should be communicated to women when offered Down's syndrome screening (DSS) or diagnosis using invasive (IDT) or non-invasive testing (NIPT). "
06/01/2015 - "The aim of the study is to study pregnant women's views on noninvasive prenatal testing (NIPT) for Down syndrome and the potential to test for a broader range of conditions. "
01/01/2015 - "The aims of this study were to test the utility of benchtop NGS platforms for NIPT for trisomy 21 using previously published z score calculation methods and to optimize the sample preparation and data analysis with use of in silico and physical size selection methods. "
01/01/2014 - "Noninvasive prenatal testing (NIPT) offers pregnant women a new risk assessment tool for fetal aneuploidy that is superior to conventional screening tests. "
10/01/2015 - "Research has progressed rapidly, with clinical data supporting laboratory studies showing that NIPT is highly sensitive and specific for fetal aneuploidy, resulting in marked uptake in the high-risk patient population. "
07/01/2015 - "The aim of this study is to explore women's opinions about the use of noninvasive prenatal testing (NIPT) to assess the risk of sex chromosome aneuploidies and microdeletion syndromes. "
07/01/2015 - "In women who had diagnostic testing with CVS during the study period, 32.4% of the aneuploidies identified would not have been detected by NIPT. "
04/01/2015 - "This study assesses the performance of noninvasive prenatal testing (NIPT) for fetal aneuploidies in a mixed risk factors pregnancy population. "
|3.||Chromosome Aberrations (Chromosome Abnormalities)
03/01/2014 - "The aim of this study was to determine the risk of missing other abnormal karyotypes of probable phenotypic significance by NIPT. "
10/01/2015 - "The potential impact of NIPT as a second-tier screen on the outcomes of high-risk pregnancies with rare chromosomal abnormalities."
02/01/2015 - "23 fetuses had other chromosomal abnormalities with an increased risk for adverse outcome that are not detectable by NIPT. "
01/01/2015 - "Current controversies in prenatal diagnosis 1: NIPT for chromosome abnormalities should be offered to women with low a priori risk."
10/01/2014 - "Combination of NIPT and CMA allows a higher prenatal detection of chromosomal abnormalities."
|4.||Spontaneous Abortion (Miscarriage)
10/01/2015 - "As a result, NIPT seems superior to other risk screening methods, such as first trimester screening, and has already resulted in a significant reduction of invasive interventions and thus intervention-related miscarriages.However"
05/01/2015 - "Test attributes were frequently cited (100%), in particular that NIPT is a blood test (89%) and avoids risk of miscarriage (56%). "
01/01/2015 - "A strategy whereby NIPT is the main method, with CVS reserved for cases with NT ≥3.0 mm, would require CVS in 21.7% of cases, identify 94.8% of significant abnormalities and avoid miscarriage in 41 pregnancies compared to CVS for all. "
01/01/2015 - "Since the introduction of the NIPT the use of these invasive tests, which are associated with a risk of miscarriage, has fallen steeply. "
12/01/2014 - "This suggests that NIPT might allow couples to decide about prenatal testing based mostly on their will to test or not, rather than largely based on fear of miscarriage risk or the uncertainty of results. "
|5.||Sex Chromosome Aberrations (Sex Chromosome Abnormality)
10/01/2015 - "This case demonstrates the possible limitations of correctly identifying sex chromosome abnormalities via NIPT. "
01/01/2015 - "Even with single nucleotide polymorphism-based NIPT, positive predictive value for detection of sex chromosome abnormalities is around 50%. "
09/01/2015 - "To evaluate the performance of Momguard, non-invasive prenatal test (NIPT) for detecting trisomy (T) 21, T18, T13, and sex-chromosome abnormalities recently developed in Korea. "
01/01/2015 - "NIPT performed at 23 weeks' gestation reported a diagnosis of monosomy X. She was offered an amniocentesis, which revealed a euploid fetus with no sex chromosome abnormalities. "
01/01/2015 - "Positive results of NIPT should be heeded with caution and an invasive diagnostic procedure should be performed, especially for rare chromosomal abnormalities and sex chromosome abnormalities where NIPT performs subpar compared to its performance for detection of trisomy 21. "
|1.||DNA (Deoxyribonucleic Acid)
|2.||Biological Markers (Surrogate Marker)
|5.||Genetic Markers (Genetic Marker)
|6.||Dihydrotachysterol (AT 10)
|8.||dimemorfan (AT 17)
|9.||tranilast (N 5')