rhamnogalacturonan II

structurally different from rhamnogalacturonan I; consists of appx 60 glycosyl residues including 2-O-methyl fucosyl, 2-O-methyl xylosyl, apiosyl & 3-C-carboxy-5-deoxy-L-xylosyl

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Hwang, Dahyun: 1 article (06/2017)
2.	Kim, Tae Young: 1 article (06/2017)
3.	Park, Hye-Ryung: 1 article (06/2017)
4.	Shin, Kwang-Soon: 1 article (06/2017)
5.	Suh, Hyung-Joo: 1 article (06/2017)
6.	Yu, Kwang-Won: 1 article (06/2017)
7.	Chen, Hubiao: 1 article (01/2017)
8.	Chen, Qilei: 1 article (01/2017)
9.	Tang, Yina: 1 article (01/2017)
10.	Yi, Tao: 1 article (01/2017)

Related Diseases

1.	Neoplasms (Cancer) 02/08/2013 - "Rhamnogalacturonan II is a Toll-like receptor 4 agonist that inhibits tumor growth by activating dendritic cell-mediated CD8+ T cells." 01/01/2017 - "Various forms of ginseng pectins rich in homogalacturonan, rhamnogalacturonan-I, rhamnogalacturonan-II, and arabinogalactan have demonstrated independent or collaborative effects on hyperglycemia, oxidative stress, immunological dysfunction, and neoplasms. " 06/01/2017 - "GTE-II consisted of 15 different sugars including rarely observed sugars such as 2-O-methyl-fucose, 2-O-methyl-xylose, apiose, aceric acid, 3-deoxy-d-manno-2-octulosonic acid, and 3-deoxy-d-lyxo-2-heptulosaric acid, which were characteristics of pectic polysaccharide rhamnogalacturonan-II. Treatment of peritoneal macrophages with GTE-II not only increased interleukin (IL)-6 and IL-12 production, but also had significantly increased tumoricidal activity against Yac-1 tumor cells than those obtained from untreated mice. "
2.	Lymphoma (Lymphomas) 02/08/2013 - "We evaluated the effectiveness of rhamnogalacturonan II (RG-II)-stimulated bone marrow-derived dendritic cells (BMDCs) vaccination on the induction of antitumor immunity in a mouse lymphoma model using EG7-lymphoma cells expressing ovalbumin (OVA). "
3.	Infections 12/01/2010 - "Borate promotes the formation of a complex between legume AGP-extensin and Rhamnogalacturonan II and enhances production of Rhizobium capsular polysaccharide during infection thread development in Pisum sativum symbiotic root nodules."
4.	Hyperglycemia 01/01/2017 - "Various forms of ginseng pectins rich in homogalacturonan, rhamnogalacturonan-I, rhamnogalacturonan-II, and arabinogalactan have demonstrated independent or collaborative effects on hyperglycemia, oxidative stress, immunological dysfunction, and neoplasms. "

Related Drugs and Biologics

1.	Polysaccharides (Glycans)
2.	Toll-Like Receptor 4
3.	Interleukin-12 (IL 12)
4.	Pectins
5.	Ovalbumin
6.	Interleukins
7.	Borates
8.	Acids
9.	Sugars
10.	3-C-carboxy-5-deoxyxylose