|1.||de Blas, E: 4 articles (05/2006 - 02/2001)|
|2.||Fernández, C: 4 articles (05/2006 - 02/2001)|
|3.||Aller, P: 4 articles (05/2006 - 02/2001)|
|4.||Domenicotti, Cinzia: 3 articles (01/2012 - 10/2005)|
|5.||Marengo, Barbara: 3 articles (01/2012 - 10/2005)|
|6.||Troyano, A: 3 articles (08/2003 - 02/2001)|
|7.||Kai, Kiyonori: 2 articles (08/2015 - 10/2008)|
|8.||Bertholet, Léa: 2 articles (04/2014 - 09/2011)|
|9.||Schenk, Françoise: 2 articles (04/2014 - 09/2011)|
|10.||Preissmann, Delphine: 2 articles (04/2014 - 09/2011)|
|1.||Spinal Cord Injuries (Spinal Cord Injury)
|3.||Breast Neoplasms (Breast Cancer)
04/01/1995 - "Preincubation of etoposide-resistant human MCF7 breast cancer cells (MCF7/VP) with buthionine sulphoximine (BSO) resulted in their sensitisation to etoposide and vincristine. "
04/01/1995 - "Buthionine sulphoximine-mediated sensitisation of etoposide-resistant human breast cancer MCF7 cells overexpressing the multidrug resistance-associated protein involves increased drug accumulation."
04/15/2010 - "In this study, inhibitors of glucose (i.e., 2-deoxy-d-glucose, 2DG) and hydroperoxide (i.e., l-buthionine-S,R-sulfoximine, BSO) metabolism were utilized in combination with a chemotherapeutic agent, paclitaxel (PTX), thought to induce oxidative stress, to treat breast cancer cells. "
05/01/2002 - "We chose to deplete glutathione in the estrogen receptor (ER)-positive MCF-7 breast cancer cell line with a gamma-glutamylcysteine transpeptidase enzyme inhibitor buthionine sulphoximine (BSO) for the purpose of studying estrogen-induced DNA damage. "
12/01/1998 - "Intracellular glutathione levels did not seem to play any role in the sensitivity of breast cancer cells to melatonin, since the addition of L-buthionine-[S,R]-sulfoximine, ethacrynic acid, or exogenous glutathione did not modify our results. "
11/01/2004 - "In this study we show that GSH depletion, produced with GSH synthesis inhibitor, L-buthionine-(S,R)-sulfoximine (BSO), induces selectively neuronal cell death in neuron/glia, but not in neuronal-enriched midbrain cultures and that cell death occurs with characteristics of necrosis and apoptosis. "
11/16/2012 - "Notably, the protective effect of hepatic GSH during Vα14iNKT cells deficiency was demonstrated by its depletion in Jα18(-/-) mice using dl-buthionine-[S,R]-sulfoximine which exacerbated hepatic oxidative and nitrosative stress as well as liver necrosis and caused mice mortality. "
02/01/2006 - "Pre-incubation with L-buthionine-(S,R)-sulfoximine (BSO) clearly switches the mode of cell death from apoptosis to necrosis at 0.01% CMI/MI. "
02/05/2001 - "However, pre-incubation with the GSH depleting agent L-buthionine-[S,R]-sulfoximine (BSO, 1 mM for 24 h) caused necrosis instead of apoptosis and failed to induce HSP70 expression. "
07/01/2009 - "Although sole administration of either AQ or L-buthionine-S,R-sulfoxinine (BSO), a well-known GSH synthesis inhibitor, produced no significant hepatotoxicity, combined administration of AQ with BSO induced hepatotoxicity characterized by centrilobular necrosis of the hepatocytes and an elevation of plasma alanine aminotransferase activity. "
07/01/2001 - "Differential effects of buthionine sulphoximine in hypoxic and non-hypoxic regions of human cervical carcinoma xenografts."
01/01/1992 - "Modulation by D,L-buthionine-S,R-sulphoximine of etoposide cytotoxicity on human non-small cell lung, ovarian and breast carcinoma cell lines."
07/01/1991 - "Treatment of A549 human lung carcinoma cells with L-buthionine-[S,R]-sulfoximine (BSO) results concomitantly in cellular glutathione (GSH) depletion and growth inhibition. "
05/01/2007 - "A reduced glutathione (GSH) inducer (N-acetyl cysteine) significantly increased while a GSH depletor (buthionine sulfoxamine) significantly decreased hSULT1E1 activity, but both failed to affect the amount of hSULT1E1 protein in human hepatocyte carcinoma Hep G2 cells. "
07/01/1986 - "Chronic aerobic exposure of A549 human lung carcinoma cell cultures to 0.1 mM L-buthionine-S,R-sulfoximine and 1 mM misonidazole, or 1 mM SR-2508 results in inhibition of cell growth and decreased clonogenic survival. "
|1.||Glutathione (Reduced Glutathione)
|2.||Peroxynitrous Acid (Peroxynitrite)
|5.||Reactive Oxygen Species (Oxygen Radicals)
|9.||Hydrogen Peroxide (Hydroperoxide)
|1.||Heterologous Transplantation (Xenotransplantation)