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methyl caffeate

from plant Gaillardia pulchella

Networked: 8 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Carboxylic Acids: 973
  - Carbocyclic Acids
    - Cinnamates: 48
      - Caffeic Acids: 15
        methyl caffeate: 8

Experts

1.	Kim, Hyun Pyo: 1 article (04/2017)
2.	Kwon, Yong Soo: 1 article (04/2017)
3.	Lim, Hyun: 1 article (04/2017)
4.	Park, Byung Kyu: 1 article (04/2017)
5.	Shin, Sook Young: 1 article (04/2017)
6.	Jin, Yin-ping: 1 article (01/2016)
7.	Qu, Zheng-yi: 1 article (01/2016)
8.	Sun, Cheng-he: 1 article (01/2016)
9.	Wang, Ying-ping: 1 article (01/2016)
10.	Yao, Chun-lin: 1 article (01/2016)

Related Diseases

1.	Body Weight (Weight, Body) 11/30/2011 - "In streptozotocin induced diabetic rats, methyl caffeate produced significant reduction in blood glucose and increased body weight. " 11/30/2011 - "The effects of oral administration of methyl caffeate (10, 20 and 40 mg/kg) for 28 days on body weight, fasting blood glucose, plasma insulin, hemoglobin, glycated hemoglobin, total protein, hepatic glycogen and carbohydrate metabolism enzymes in streptozotocin induced diabetic rats were investigated. "
2.	Aberrant Crypt Foci 09/15/1993 - "The present study was designed to investigate (a) the inhibitory effects of methyl caffeate (MC) and phenylethyl caffeate (PEC) on azoxymethane (AOM)-induced ornithine decarboxylase (ODC), tyrosine protein kinase (TPK), and arachidonic acid metabolism in liver and colonic mucosa of male F344 rats, (b) the effects of caffeic acid, MC, PEC, phenylethyl-3-methylcaffeate (PEMC), and phenylethyl dimethylcaffeate (PEDMC) on in vitro arachidonic acid metabolism in liver and colonic mucosa, and (c) the effects of PEC, PEMC, and PEDMC on AOM-induced aberrant crypt foci (ACF) formation in the colon of F344 rats. "
3.	Neoplasms (Cancer) 12/01/1994 - "Gallic acid, methyl caffeate, protocatechuic acid and pedunculagin mildly inhibited the survival of PC14 and MKN45 human cancer cell. " 12/01/2022 - "Four known compounds with cytotoxic effects on cancer cell lines were isolated from the most active fraction, including 5-Hydroxy-3',4',6,7-tetramethoxyflavone (eupatilin 7-methyl ether), 5-hydroxy 3,3',4',6,7-pentamethoxy-flavone (artemetin), 6-methoxy-7-hydroxycoumarin (scopoletin), and methyl caffeate. "
4.	Breast Neoplasms (Breast Cancer) 01/15/2013 - "Together, our data indicate that the oxidative dimerization product of methyl caffeate can inhibit breast cancer cell growth at a concentration adequate for pharmacological use." 01/15/2013 - "Antiproliferative and apoptotic effects of the oxidative dimerization product of methyl caffeate on human breast cancer cells." 01/15/2013 - "The product of the oxidative dimerization of methyl caffeate, 1-phenylnaphthalene lignan, was found to induce a strong decrease in breast cancer cell number (IC(50) ~1 μM) and was selected for further investigation. " 11/20/2002 - "Six of these antioxidants were found to reduce menadione-induced DNA damage in cultured S30 breast cancer cells with the following order of potency: methyl caffeate (2) > caffeic acid (1) > ferulic acid (3) > cimiracemate A (9) > cimiracemate B (10) > fukinolic acid (5). "
5.	Lewis Lung Carcinoma 01/01/2016 - "Results showed that 3'-O-methyl isocrenatoside (1) and methyl caffeate (2) exhibited significant cytotoxicity, with IC50 values of 71.89, 36.97 μg/mL and 32.32, 34.58 μg/mL against the B16F10 murine melanoma and Lewis lung carcinoma cell lines, respectively."

Related Drugs and Biologics

1.	Streptozocin (Streptozotocin)
2.	Blood Glucose (Blood Sugar)
3.	caffeic acid
4.	Arachidonic Acid (Vitamin F)
5.	Protein-Tyrosine Kinases (Tyrosine Kinase)
6.	Ornithine Decarboxylase (Decarboxylase, Ornithine)
7.	Azoxymethane
8.	Vitamin K 3 (Menadione)
9.	Lignans
10.	Scopoletin

Related Therapies and Procedures

1.	Oral Administration