09/01/1987 - "Previous studies suggested that RA 233 and RX-RA 85 increase cAMP levels in 2 other cell clones of rat 13762NF mammary adenocarcinoma by inhibiting phosphodiesterases. "
09/01/1987 - "The pyrimido-pyrimidine derivatives RA 233 and RX-RA 85 affect growth and cytoskeletal organization of rat mammary adenocarcinoma cells."
09/01/1987 - "Using an endothelial cell momolayer attachment assay we have investigated the effects of RX-RA 85 on tumor cell and endothelial cell properties. "
09/01/1987 - "Effects of the pyrimido-pyrimidine derivative RX-RA 85 on metastatic tumor cell-vascular endothelial cell interactions."
09/01/1987 - "The pyrimido-pyrimidine derivatives RA 233 and RX-RA 85, which are potent inhibitors of platelet and tumor phosphodiesterase, were developed as antitumor agents. "
|3.||Melanoma (Melanoma, Malignant)
|1.||Phosphoric Diester Hydrolases (Phosphodiesterases)
|3.||Antineoplastic Agents (Antineoplastics)