|1.||Elumalai, Perumal: 3 articles (12/2014 - 04/2014)|
|2.||Gupta, Subash C: 3 articles (08/2013 - 11/2010)|
|3.||Aggarwal, Bharat B: 3 articles (08/2013 - 11/2010)|
|4.||Nagini, S: 3 articles (08/2010 - 06/2009)|
|5.||Arunakaran, Jagadeesan: 2 articles (12/2014 - 07/2014)|
|6.||Elumalai, P: 2 articles (12/2014 - 11/2012)|
|7.||Arunakaran, J: 2 articles (12/2014 - 11/2012)|
|8.||Sharmila, G: 2 articles (12/2014 - 11/2012)|
|9.||Arunkumar, Ramachandran: 2 articles (07/2014 - 04/2014)|
|10.||Sharmila, Govindaraj: 2 articles (07/2014 - 04/2014)|
|1.||Breast Neoplasms (Breast Cancer)
07/01/2014 - "Nimbolide decreases the proliferation of breast cancer cells by modulating the IGF signalling molecules, which could be very useful for the breast cancer treatment."
12/01/2014 - "Our previous studies have shown that nimbolide elicits pleiotropic effects on breast cancer cells; however, its roles in invasion and migration have not previously been fully elucidated. "
07/01/2014 - "The present study was aimed to investigate the effect of nimbolide on IGF signalling and cell cycle arrest in MCF-7 and MDA-MB-231 breast cancer cell lines. "
04/01/2015 - "Nimbolide inhibits invasion of breast cancer."
12/01/2014 - "Nimbolide inhibited breast cancer cell migration and invasion as shown in transwell invasion and wound healing assays. "
06/01/2009 - "The results of the present study suggest that nimbolide has immense potential in cancer prevention and therapy based on its antiproliferative and apoptosis inducing effects."
09/01/2015 - "Nimbolide is a tetranortriterpenoid isolated from the leaves and flowers of Azadirachta indica which has been shown to exhibit anticancer, antioxidant, anti-inflammatory, and anti-invasive properties in a variety of cancer cells. "
01/01/2015 - "Nimbolide has potential as an anti-tumor drug given its multifunctional effects in OS. "
12/01/2014 - "This review highlights the current knowledge on the molecular targets that contribute to the observed anticancer activity of nimbolide related to induction of apoptosis and cell cycle arrest; and inhibition of signaling pathways related to cancer progression. "
12/01/2014 - "Review on molecular and chemopreventive potential of nimbolide in cancer."
|3.||Neoplasm Metastasis (Metastasis)
08/01/2014 - "The preclinical and mechanistic studies carried over the decades have shown that nimbolide inhibits tumorigenesis and metastasis without any toxicity and unwanted side effects. "
01/01/2015 - "We also determined that Nimbolide inhibits cell migration, which is crucial for metastasis, by reducing the expression of integrin αvβ5. "
12/01/2014 - "The previous studies carried out over the decades have shown that nimbolide inhibits cell proliferation and metastasis of cancer cells. "
08/01/2014 - "Nimbolide exhibits anticancer activity through selective modulation of multiple cell signaling pathways linked to inflammation, survival, growth, invasion, angiogenesis and metastasis. "
12/01/2014 - "These results clearly proved inhibitory effects of nimbolide on tumour cell invasion and migration by down-regulating proteins critically involved in regulation of cell invasion and metastasis, suggesting a possible therapeutic role of nimbolide for breast cancer."
|4.||Colorectal Neoplasms (Colorectal Cancer)
08/15/2013 - "Our studies provide evidence that nimbolide can suppress the growth of human colorectal cancer through modulation of the proinflammatory microenvironment."
08/15/2013 - "Whether nimbolide, a limonoid triterpene, can inhibit the growth of colorectal cancer was investigated in the present study. "
08/15/2013 - "Nimbolide, a limonoid triterpene, inhibits growth of human colorectal cancer xenografts by suppressing the proinflammatory microenvironment."
08/15/2013 - "Nimbolide inhibited proliferation, induced apoptosis, and suppressed NF-κB activation and NF-κB-regulated tumorigenic proteins in colorectal cancer cells. "
08/15/2013 - "The effect of nimbolide on the tumor growth in vivo was examined in colorectal cancer xenografts in a nude mouse model. "
|5.||Osteosarcoma (Osteogenic Sarcoma)
|1.||azadirachtin (azadirachtin A)
|3.||Proteins (Proteins, Gene)
|4.||Messenger RNA (mRNA)
|5.||Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)
|7.||DNA (Deoxyribonucleic Acid)
|9.||Fas Ligand Protein (Fas Ligand)
|10.||Death Domain Receptors
|1.||Heterologous Transplantation (Xenotransplantation)