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esaprazole

RN given refers to parent cpd; structure in first source

Also Known As:

N-((N-cyclohexylcarbamoyl)methyl)piperazine; esaprazole monohydrochloride; hexaprazol

Networked: 5 relevant articles (0 outcomes, 3 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Piperazines: 26
    - esaprazole: 5

Experts

1.	Elbrønd-Bek, Heidi: 1 article (06/2013)
2.	Jørgensen, Signe Humle: 1 article (06/2013)
3.	Kelly, Nicholas M: 1 article (06/2013)
4.	Weidner, Morten Sloth: 1 article (06/2013)
5.	Wellejus, Anja: 1 article (06/2013)

Related Diseases

1.	Stomach Ulcer (Gastric Ulcer) 01/01/1987 - "Although the study involved only a small number of patients, the findings obtained indicate the potential usefulness of esaprazole in the treatment of gastric ulcer." 01/01/1987 - "Esaprazole in the treatment of gastric ulcer: preliminary clinical trial." 01/01/1987 - "The activity and tolerability of esaprazole administered once a day at doses of 900 and 1350 mg/day in the treatment of gastric ulcer were evaluated in a preliminary study carried out in 47 patients. "
2.	Gastritis 04/30/1991 - "The results of the present study suggest that esaprazole, a new gastroprotective drug, may have a role in the therapy of dyspeptic patients with chronic superficial gastritis." 04/30/1991 - "[Esaprazole vs sulglicotide in the treatment of dyspeptic patients with chronic superficial gastritis of the antrum]." 04/30/1991 - "Fifty dyspeptic patients with histologically proven chronic superficial antral gastritis were treated for 6 weeks, in a randomized single-blind study, with esaprazole (450 mg bid) or sulglicotide (200 mg tid). "
3.	Duodenal Ulcer (Curling's Ulcer) 01/01/1993 - "To study the effect of Esaprazole, a new antiulcer drug, on acid, peptic and alkaline secretion a modified gastric acid test was performed in 18 duodenal ulcer patients. " 01/01/1993 - "Esaprazole effect on acid, peptic and alkaline secretion in duodenal ulcer patients."
4.	Ulcer 06/01/2013 - "Esaprazole, a molecule previously acknowledged to protect against stomach and intestinal ulcers was surprisingly discovered to have neuroprotective activities and σ1 binding in vitro. "
5.	Gastric Fistula 04/01/1993 - "Esaprazole affected in a different extent the tests performed on dogs with a gastric fistula. " 04/01/1993 - "The effects of esaprazole, a novel antiulcer drug, on gastric acid secretion and plasma gastrin levels were investigated in dogs provided with a gastric fistula or Heidenhain pouch. "

Related Drugs and Biologics

1.	Acids
2.	OF 900
3.	Gastrins
4.	Antral
5.	sulglicotide

Related Therapies and Procedures

1.	Therapeutics