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splenopentin
see also BCH 069 which is a modified pentapeptide from splenin
Also Known As:
Arg-Lys-Glu-Val-Tyr; splenin pentapeptide (32-36); thymopoietin III pentapeptide (32-36)
Networked:
6
relevant articles (
1
outcomes,
0
trials/studies)
Relationship Network
Bio-Agent Context: Research Results
Amino Acids, Peptides, and Proteins: 1
Peptides: 82426
Peptide Fragments: 373
splenopentin: 6
Hormones, Hormone Substitutes, and Hormone Antagonists
Hormones: 80400
Thymus Hormones: 55
Thymopoietins: 58
splenopentin: 6
Related Diseases
1.
Inflammation (Inflammations)
01/01/1992 - "
These findings suggest that treatment with diacetyl-splenopentin normalizes the immune regulation, which is disturbed in the early phase of inflammation.
"
01/01/1992 - "
Long-term treatment with the immunomodulator diacetyl-splenopentin reduces the severity of chronic joint inflammation and cartilage destruction in rabbits with antigen-induced arthritis.
"
2.
Arthritis (Polyarthritis)
01/01/1992 - "
Effects of the immunomodulator diacetyl-splenopentin on antigen-induced arthritis in rabbits.
"
01/01/1992 - "
Long-term treatment with the immunomodulator diacetyl-splenopentin reduces the severity of chronic joint inflammation and cartilage destruction in rabbits with antigen-induced arthritis.
"
3.
Psoriatic Arthritis
01/01/1990 - "
Therefore we conclude that splenopentin alone is not a sufficient therapeutic drug in patients suffering from psoriatic arthritis.
"
01/01/1990 - "
8 patients with confirmed psoriatic arthritis were treated with splenopentin for 12 months.
"
01/01/1990 - "
[Therapeutic use of splenopentin (DA SP-5) in patients with psoriasis arthropathica].
"
4.
Neoplasm Metastasis (Metastasis)
01/01/1991 - "
Similar treatment of mice with two other immunomodulators (thymalin and diacetyl-splenopentin 5) was practically without effect on metastasis formation.
"
5.
Leukemia
01/01/1989 - "
A combined treatment with ambazone and immunomodulators (thymalin or a splenopentin derivative) failed to improve the antileukemic effect in young and old leukemia P388-bearing mice.
"
Related Drugs and Biologics
1.
Immunologic Factors (Immunomodulators)
2.
Diacetyl (Biacetyl)
3.
Antigens
4.
thymalin
5.
Therapeutic Uses
6.
BCH 069
7.
1,4-benzoquinone guanylhydrazone thiosemicarbazone (ambazone)