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splenopentin

see also BCH 069 which is a modified pentapeptide from splenin

Also Known As:

Arg-Lys-Glu-Val-Tyr; splenin pentapeptide (32-36); thymopoietin III pentapeptide (32-36)

Networked: 6 relevant articles (1 outcomes, 0 trials/studies)

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Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Peptide Fragments: 373
    - splenopentin: 6
Hormones, Hormone Substitutes, and Hormone Antagonists
- Hormones: 80400
  - Thymus Hormones: 55
    - Thymopoietins: 58
      - splenopentin: 6

Related Diseases

1.	Inflammation (Inflammations) 01/01/1992 - "These findings suggest that treatment with diacetyl-splenopentin normalizes the immune regulation, which is disturbed in the early phase of inflammation. " 01/01/1992 - "Long-term treatment with the immunomodulator diacetyl-splenopentin reduces the severity of chronic joint inflammation and cartilage destruction in rabbits with antigen-induced arthritis. "
2.	Arthritis (Polyarthritis) 01/01/1992 - "Effects of the immunomodulator diacetyl-splenopentin on antigen-induced arthritis in rabbits." 01/01/1992 - "Long-term treatment with the immunomodulator diacetyl-splenopentin reduces the severity of chronic joint inflammation and cartilage destruction in rabbits with antigen-induced arthritis. "
3.	Psoriatic Arthritis 01/01/1990 - "Therefore we conclude that splenopentin alone is not a sufficient therapeutic drug in patients suffering from psoriatic arthritis." 01/01/1990 - "8 patients with confirmed psoriatic arthritis were treated with splenopentin for 12 months. " 01/01/1990 - "[Therapeutic use of splenopentin (DA SP-5) in patients with psoriasis arthropathica]."
4.	Neoplasm Metastasis (Metastasis) 01/01/1991 - "Similar treatment of mice with two other immunomodulators (thymalin and diacetyl-splenopentin 5) was practically without effect on metastasis formation. "
5.	Leukemia 01/01/1989 - "A combined treatment with ambazone and immunomodulators (thymalin or a splenopentin derivative) failed to improve the antileukemic effect in young and old leukemia P388-bearing mice."

Related Drugs and Biologics

1.	Immunologic Factors (Immunomodulators)
2.	Diacetyl (Biacetyl)
3.	Antigens
4.	thymalin
5.	Therapeutic Uses
6.	BCH 069
7.	1,4-benzoquinone guanylhydrazone thiosemicarbazone (ambazone)