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complement C5a-inhibitors

found in normal peritoneal & synovial fluids; deficiency causes familial Mediterranean fever; also found in Streptococcus; have capability of inactivating complement-derived chemotactic factors; do not use /antag

Also Known As:

C5a-inhibitor; C5a-inhibitors; complement 5a-inhibitors; group A streptococcal C5a inactivator; group B streptococcal C5a inactivator

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Hydrolases: 2166
    - Peptide Hydrolases: 23957
      - Serine Proteases: 3726
        Serine Endopeptidases: 11
        complement C5a-inhibitors: 2
      - Endopeptidases: 633
        Serine Endopeptidases: 11
        complement C5a-inhibitors: 2

Related Diseases

1.

Familial Mediterranean Fever (Periodic Disease)

08/02/1984 - "C5a-inhibitor deficiency--a role in familial Mediterranean fever?"
08/02/1984 - "We suggest that C5a-inhibitor deficiency in joint and peritoneal fluids from patients with familial Mediterranean fever may have a role in the pathogenesis of the inflammatory attacks characteristic of this disease."
08/02/1984 - "C5a-inhibitor deficiency in peritoneal fluids from patients with familial Mediterranean fever."