protozoan amoebapore proteins

ion-channel forming material in virulent strains of Entamoeba histolytica; may be responsible for many symptoms associated with amoebic dysentery; MW 13,000; also found in Naegleria

Also Known As:

Networked: 8 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	García de León, Ma Carmen: 1 article (01/2017)
2.	González, Enrique: 1 article (01/2017)
3.	Gudiño-Zayas, Marco: 1 article (01/2017)
4.	Hernández, Eric: 1 article (01/2017)
5.	Magaña, Ulises: 1 article (01/2017)
6.	Maldonado, Héctor: 1 article (01/2017)
7.	Morán, Patricia: 1 article (01/2017)
8.	Nieves, Miriam: 1 article (01/2017)
9.	Partida, Oswaldo: 1 article (01/2017)
10.	Rojas-Velázquez, Liliana: 1 article (01/2017)

Related Diseases

1.	Neoplasms (Cancer) 05/01/2009 - "In vivo targeted killing of prostate tumor cells by a synthetic amoebapore helix 3 peptide modified with two γ-linked glutamate residues at the COOH terminus." 09/15/2001 - "In vitro targeted killing of prostate tumor cells by a synthetic amoebapore helix 3 peptide modified with two gamma-linked glutamate residues at the COOH terminus." 09/15/2001 - "To target prostate tumor cells, a novel procytolytic peptide was designed with a backbone consisting of an amoebapore H3 domain modified by two gamma-linked glutamate residues at the epsilon-amino group of the COOH-terminal lysine residue. "
2.	Infections 12/01/2012 - "To do this, the PCLS was analyzed for the expression of amoebapore and cysteine proteinases 1 and 5, three of the most studied virulence factors of Entamoeba histolytica, as well as the induction of apoptosis and cytokines production in response to the ex vivo infection. " 01/01/2017 - "dispar-infected PCLS were analyzed at different post-infection times (0, 1, 3, 24 and 48 h) to evaluate the relation between tissue damage and the expression of genes associated with three factors: a) parasite survival (peroxiredoxin, superoxide dismutase and 70 kDa heat shock protein), b) parasite virulence (EhGal/GalNAc lectin, amoebapore, cysteine proteases and calreticulin), and c) the host inflammatory response (various cytokines). "
3.	Amebic Dysentery (Amoebic Dysentery) 02/01/2004 - "Here we tested the virulence of amoebapore A(-) trophozoites in models of the two major forms of amebic disease: amebic liver abscess and amebic colitis. " 11/01/2009 - "Amoebapore A is a pore-forming protein produced by the pathogenic parasite Entamoeba histolytica, which causes human amoebic dysentery. "
4.	Starvation 12/01/2011 - "URE3-BP, KRiP1 and Lgl1 proteins are upregulated while virulence factors amoebapore A and cysteine proteinase A5 are downregulated by glucose starvation. "
5.	Amebic Liver Abscess 02/01/2004 - "We demonstrate that amoebapore expression is required for full virulence in the SCID mouse model of amebic liver abscess, but E. " 02/01/2004 - "Here we tested the virulence of amoebapore A(-) trophozoites in models of the two major forms of amebic disease: amebic liver abscess and amebic colitis. "

Related Drugs and Biologics

1.	Cysteine Proteases (Cysteine Protease)
2.	Virulence Factors (Pathogenicity Factors)
3.	Glutamic Acid (Glutamate)
4.	Cytokines
5.	Proteins (Proteins, Gene)
6.	Peptides (Polypeptides)
7.	Peroxiredoxins
8.	Calreticulin
9.	Lectins
10.	Superoxide Dismutase