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desciclovir

active prodrug of acyclovir

Also Known As:

2-((2-amino-9H-purin-9-yl)methoxy)-ethanol; 2-amino-9-(2-hydroxyethyl)methyl-9H-purine; 6-deoxyacyclovir; BW A515U

Networked: 9 relevant articles (1 outcomes, 3 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Purines: 651
      - Purinones: 2
        Hypoxanthines: 1
        Guanine: 1793
        Acyclovir: 4814
        desciclovir: 9

Related Diseases

1.	Epstein-Barr Virus Infections 01/01/1990 - "The histological features of HL were significantly diminished in patients on desciclovir, and cytochemical, in situ hybridization, and ultrastructural studies showed that EBV infection was eliminated or dramatically reduced in the desciclovir group only. " 01/01/1990 - "Efficacy of desciclovir in the treatment of Epstein-Barr virus infection in oral hairy leukoplakia." 01/01/1990 - "The efficacy of desciclovir, an analog of acyclovir, in eliminating lesions of oral hairy leukoplakia (HL) and suppressing Epstein-Barr virus (EBV) infection was evaluated in a double-blind, placebo-controlled study of 14 patients. "
2.	Hairy Leukoplakia 01/01/1990 - "Efficacy of desciclovir in the treatment of Epstein-Barr virus infection in oral hairy leukoplakia." 01/01/1990 - "The efficacy of desciclovir, an analog of acyclovir, in eliminating lesions of oral hairy leukoplakia (HL) and suppressing Epstein-Barr virus (EBV) infection was evaluated in a double-blind, placebo-controlled study of 14 patients. "
3.	Hepatitis 03/01/1987 - "The efficient hepatic conversion of 6-deoxyacyclovir to the active antiviral drug, acyclovir, provides a rationale for trials of oral 6-deoxyacyclovir in the treatment of chronic type B hepatitis." 08/29/1988 - "For patients with chronic hepatitis B e (HBe)-positive hepatitis, long-term results of pilot studies with lymphoblastoid interferon-alpha, acyclovir, or a combination, and of a randomized controlled trial of interferon/desciclovir combination therapy are presented. "
4.	Herpes Zoster 11/01/1987 - "Open study of 2-amino-9-(hydroxyethoxymethyl)-9H-purine (desciclovir) in the treatment of herpes zoster." 11/01/1987 - "An oral pro-drug of acyclovir, 2-amino-9-(2-hydroxyethoxymethyl)-9H-purine (desciclovir) was evaluated in an open study comprising of 20 patients with herpes zoster. "
5.	Chronic Hepatitis B 01/01/1986 - "A pilot study of BW A515U (6-deoxyacyclovir) in chronic hepatitis B virus infection." 08/29/1988 - "For patients with chronic hepatitis B e (HBe)-positive hepatitis, long-term results of pilot studies with lymphoblastoid interferon-alpha, acyclovir, or a combination, and of a randomized controlled trial of interferon/desciclovir combination therapy are presented. "

Related Drugs and Biologics

1.	Acyclovir (Aciclovir)
2.	Prodrugs
3.	Antiviral Agents (Antivirals)
4.	Interferon-alpha (Interferon Alfa)
5.	Vidarabine (Vira-A)
6.	Interferons
7.	Idoxuridine (Stoxil)
8.	Bromodeoxyuridine (BrdU)
9.	Adenosine Monophosphate (AMP)
10.	Famciclovir (Famvir)

Related Therapies and Procedures

1.	Therapeutics