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ornithine transporter (ornithine translocase)

Also Known As:
ornithine translocase; ornithine carrier; ornithine translocator
Networked: 9 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Tsujino, Seiichi: 2 articles (03/2004 - 01/2002)
2. Kanazawa, Naomi: 2 articles (03/2004 - 01/2002)
3. Tsujino, S: 2 articles (11/2001 - 01/2001)
4. Kanazawa, N: 2 articles (11/2001 - 01/2001)
5. Miyamoto, T: 2 articles (11/2001 - 01/2001)
6. Pierri, Ciro L: 1 article (05/2015)
7. Palmieri, Luigi: 1 article (05/2015)
8. Marobbio, Carlo M T: 1 article (05/2015)
9. Punzi, Giuseppe: 1 article (05/2015)
10. Panaro, Maria A: 1 article (05/2015)

Related Diseases

1. Hyperammonemia
12/01/2010 - "Mutations in the SLC25A15 gene, encoding the human inner mitochondrial membrane ornithine transporter, are thought to be responsible for hyperornithinemia-hyperammonemia-homocitrullinemia (HHH) syndrome, a rare autosomal recessive condition. "
12/01/2005 - "Mutations in the mitochondrial ornithine transporter result in hyperammonemia, hyperornithinemia, homocitrullinuria syndrome, a disorder of the urea cycle. "
03/15/2004 - "Hyperornithinemia, hyperammonemia, and homocitrullinuria (HHH) syndrome is caused by mutations in the SLC25A15 (ORNT1) gene encoding the mitochondrial ornithine transporter, but the mechanism of pathogenesis of the encephalopathy, spastic paraparesis and hepatopathy remains undetermined. "
06/01/2011 - "Increased urinary KGM was also noted in other patients with primary hyperammonemia, including three patients with a defect resulting in lysinuric protein intolerance and one of two patients with a defect in the ornithine transporter I. These findings indicate disturbances in nitrogen metabolism, most probably at the level of glutamine metabolism in primary hyperammonemia diseases. "
11/01/2001 - "Mitochondrial ornithine transporter deficiency has been called HHH syndrome, because this disorder is characterized by three biochemical abnormalities; hyperornithinemia, hyperammonemia, and homocitrullinuria, and presents with various neurological symptoms; mental retardation, spastic paraparesis with pyramidal signs, cerebellar ataxia and episodic disturbance of consciousness or coma due to hyperammonemia. "
2. Spastic Paraparesis
3. Mental Retardation (Idiocy)
4. Coma (Comas)
5. Cerebellar Ataxia (Dysmetria)

Related Drugs and Biologics

1. HHH syndrome
2. Urea (Carbamide)
3. Ornithine
4. Nitrogen
5. Glutamine (L-Glutamine)
6. Citrulline