acridone

07/01/2014 - "The goal of this study was to assess efficacy of acridone acetic acid, sodium salt (Na-AAA), an immunomodulating compound with favorable safety profile, in stabilizing active vitiligo, and to reveal prognostic factors of treatment outcome. "
07/01/2014 - "In conclusion, acridone acetic acid, sodium salt, emerges as an efficient option for stopping vitiligo progression. "
07/01/2014 - "Acridone acetic acid, sodium salt, as an agent to stop vitiligo progression: a pilot study."

01/01/2021 - "In this study a novel mathematical model has been developed to explore the various drug combinations that may be useful for the treatment of resistant Glioma and show that the combinations of TMZ and Acridone derivatives have a synergistic effect. "
01/01/2021 - "Study of Combinatorial Drug Synergy of Novel Acridone Derivatives With Temozolomide Using in-silico and in-vitro Methods in the Treatment of Drug-Resistant Glioma."

11/01/2020 - "Previously, we described a novel antimalarial acridone chemotype that is potent against both blood-stage and liver-stage malaria parasites. "
11/01/2019 - "We have discovered a novel antimalarial acridone chemotype with dual-stage activity against both liver-stage and blood-stage malaria. "
02/01/1991 - "Acridone alkaloids isolated from plants of the family Rutaceae have antiplasmodial activity in rodent models of malaria. "
01/01/1989 - "In vitro and in vivo activities of atalaphillinine and related acridone alkaloids against rodent malaria."

01/01/2021 - "To screen in vitro anti-cancer activity against Cdc25b and SHP1 of new acridone derivatives and preliminary study on the structure-activity relationship. "
02/01/2018 - "In the present study, the anti-tumor function and the underlying mechanisms of acridone were evaluated in vitro. "
07/17/2011 - "Cytotoxicity studies of some novel fluoro acridone derivatives against sensitive and resistant cancer cell lines and their mechanistic studies."
09/05/2022 - "Here, the authors have attempted to compile and make some recommendations of acridone based derivatives concerning their cancer biological targets and in vitro-cytotoxicity based on drug design and novelty to increase their therapeutic potential. "
09/05/2022 - "A comprehensive review on acridone based derivatives as future anti-cancer agents and their structure activity relationships."

04/01/2023 - "Evaluation of N 10 -substituted acridone-based derivatives as AKT inhibitors against breast cancer cells: in vitro and molecular docking studies."
02/01/2018 - "These findings suggested that acridone is a potential agent in the treatment of human breast cancer."
02/01/2018 - "However, the anticancer effect and the underlying mechanisms of acridone on breast cancer cells remains unclear. "
01/01/2018 - "The results suggested that acridone could serve as a chemotherapeutic agent for treatment of breast cancer in vivo."
01/01/2018 - "Inhibition effects of acridone on the growth of breast cancer cells in vivo."