uterine-derived cell growth factor

from pregnant sheep uteri; MW 4200-6200; mitogenic factor in rat mammary tumor cells; promotes growth of uterine-derived tumor cells & pituitary cells

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Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Related Diseases

1.

Neoplasms (Cancer) 04/10/1984 - "UDGF also promoted growth of uterine-derived tumor cells and the GH3/C14 rat pituitary line. " 04/10/1984 - "Measuring growth as an increase in cell number, UDGF supported the logarithmic growth of the MTW9/PL rat mammary tumor cells over 6 days; other known hormones and growth factors were not able to substitute for the UDGF mitogenic action on MTW9/PL cells. " 04/10/1984 - "The UDGF isolated showed marked cell-type specificity for established cell lines that were derived from estrogen-responsive tumors; purified sheep UDGF was mitogenic for MTW9/PL rat mammary tumor cells (at 10(-10) to 10(-9) M concentrations) while showing no mitogenic activity toward normal rat diploid fibroblasts. "

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