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2-ethylhexanoic acid

structure in first source; wood preservative; 2-ethylhexanoic acid is active ingredient in Sinesto B

Also Known As:

Sinesto B

Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Carboxylic Acids: 973
  - Acyclic Acids
    - Caproates: 7
      - 2-ethylhexanoic acid: 2
Lipids: 114793
- Fatty Acids: 27405
  - Volatile Fatty Acids: 3052
    - Caproates: 7
      - 2-ethylhexanoic acid: 2

Related Diseases

1.	Neoplasms (Cancer) 01/01/1988 - " When the Population Council evaluated the tests leading to the EPA's request for further studies, it found that in laboratory tests using compounds related to 2-ethylhexanoic acid, the lowest doses causing cancer in rats and mice were, by body weight, 13,000 times as much per day as the total potential amount of the component in Norplant-R-2. "
2.	Body Weight (Weight, Body) 01/01/1988 - " When the Population Council evaluated the tests leading to the EPA's request for further studies, it found that in laboratory tests using compounds related to 2-ethylhexanoic acid, the lowest doses causing cancer in rats and mice were, by body weight, 13,000 times as much per day as the total potential amount of the component in Norplant-R-2. "
3.	Hepatocellular Carcinoma (Hepatoma) 01/01/1988 - " The EPA request was based on reports that high doses of the substance, 2-ethylhexanoic acid, may cause hepatocellular carcinoma and congenital malformations in laboratory rodents. "
4.	Glioma (Gliomas) 02/01/1997 - "The majority of the compounds significantly inhibited C6 glioma proliferation, the most potent compounds being ranked as octanoic acid > 2-propylhexanoic acid > or = 2-ethylhexanoic acid > or = valproic acid. " 02/01/1997 - "In this lectin affinity assay, the most potent analogues to significantly attenuate the affinity of exposed C6 glioma cells for concanavalin A lectin-coated plastic included 2-butylhexanoic acid, 2-propyl-4-pentenoic acid, 2-propylhexanoic acid and 2-ethylhexanoic acid in a manner which can be related to their relative teratogenic potencies in vivo. "

Related Drugs and Biologics

1.	Lectins
2.	Valproic Acid (Depakote)
3.	Plastics
4.	Concanavalin A
5.	Acids
6.	2-propyl-4-pentenoic acid
7.	octanoic acid (caprylic acid)