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3'-nucleotidase

Also Known As:

2',3'-cyclic phosphodiesterase; 3'-nuclease; 3'-nucleotidase-nuclease

Networked: 5 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Hydrolases: 2166
    - Esterases: 1574
      - Phosphoric Monoester Hydrolases: 7477
        Nucleotidases: 50
        3'-nucleotidase: 5

Experts

1.	York, John D: 3 articles (01/2020 - 02/2005)
2.	Hale, Andrew T: 2 articles (01/2020 - 01/2018)
3.	Hudson, Benjamin H: 2 articles (01/2020 - 01/2018)
4.	Brown, Rachel E: 1 article (01/2020)
5.	Luka, Zigmund: 1 article (01/2020)
6.	Matta, Pranathi: 1 article (01/2020)
7.	Williams, Christopher S: 1 article (01/2020)
8.	Irving, Ryan P: 1 article (01/2018)
9.	Li, Shenglan: 1 article (01/2018)
10.	Dela Cruz, June: 1 article (02/2005)

Related Diseases

1.	Starvation 01/04/1985 - "Enzyme regulation in a trypanosomatid: effect of purine starvation on levels of 3'-nucleotidase activity." 02/01/2000 - "Analysis of monomeric products of sequential RNA hydrolysis with purified RNase LE, purified extracellular phosphodiesterase, and cleared -Pi culture medium as a source of 3'-nucleotidase activity indicates that cyclic nucleotide phosphodiesterase functions as an accessory ribonucleolytic activity that effectively hydrolyzes primary products of RNase LE to substrates for phosphate-starvation-inducible phosphomonoesterases. "
2.	Iron-Deficiency Anemia (Anemia, Iron Deficiency) 01/01/2018 - "We report that loss of a key enzymatic component of the pathway, bisphosphate 3'-nucleotidase (Bpnt1), in mice, both whole animal and intestine-specific, leads to iron-deficiency anemia. " 01/01/2020 - "We recently reported that mice lacking bisphosphate 3'-nucleotidase (BPNT1), a key regulator of sulfur assimilation, develop iron-deficiency anemia (IDA) and anasarca. "
3.	Edema (Dropsy) 01/01/2020 - "We recently reported that mice lacking bisphosphate 3'-nucleotidase (BPNT1), a key regulator of sulfur assimilation, develop iron-deficiency anemia (IDA) and anasarca. "
4.	Bipolar Disorder (Manic Depressive Psychosis) 02/18/2005 - "Collectively, our data support a role for 3'-nucleotidase activity and PAP metabolism in aspects of lithium's mechanism of action and provide a platform for development of novel pharmacological modulators aimed at improving therapies for the treatment of bipolar disorder."

Related Drugs and Biologics

1.	RNA (Ribonucleic Acid)
2.	Ribonucleases (Ribonuclease)
3.	Phosphoric Monoester Hydrolases (Phosphatases)
4.	Phosphoric Diester Hydrolases (Phosphodiesterases)
5.	Phosphates (Orthophosphate)
6.	Cyclic Nucleotides
7.	Sulfur
8.	Lithium
9.	Enzymes
10.	purine

Related Therapies and Procedures

1.	Therapeutics