destruxin A

cyclopeptide from entomopathogenic fungus Metarhyzium anisopliae; structure given in first source

Also Known As:

destruxin DA; cyclo(N-methyl-L-alanyl-beta-alanyl-(2R)-2-hydroxy-4-pentenoyl-L-prolyl-L-isoleucyl-N-methyl-L-valyl)

Networked: 6 relevant articles (0 outcomes, 1 trials/studies)

1.	Infections 10/01/2017 - "Quantification of fungal growth and destruxin A during infection of Galleria mellonella larvae by Metarhizium brunneum." 10/01/2017 - "Although several studies focus on the production of destruxin A in culture media, few studies examine destruxin A in vivo during host infection. " 11/01/1997 - "The effects of Metarhizium anisopliae infection and three different secondary metabolites released by the fungus, destruxin A and E and cytochalasin D, on the morphology and cytoskeleton of plasmatocytes of the greater wax moth Galleria mellonella were studied. " 01/01/2017 - "xylostella to limit the infection of fungal peptide destruxin A by increasing the activity of antimicrobial peptides."
2.	Paralysis (Palsy) 01/01/2023 - "The injection of Destruxin A leads to the rapid paralysis of flies, whether wild type (WT) or mutant. "
3.	Hepatocellular Carcinoma (Hepatoma) 12/01/2013 - "Destruxin A, destruxin B and destruxin E isolated from entomopathogenic fungus Metarhizium anisopliae showed a strong suppressive effect on the replication of hepatitis B virus (HBV) in human hepatoma cells. "
4.	Fever (Fevers) 10/01/2011 - "The inhibitory effect of the fungal toxin, destruxin A, on behavioural fever in the desert locust."