|1.||Cummings, Richard D: 8 articles (01/2014 - 02/2004)|
|2.||Nakada, Hiroshi: 7 articles (02/2015 - 11/2006)|
|3.||Ju, Tongzhong: 7 articles (01/2014 - 02/2004)|
|4.||Osinaga, Eduardo: 7 articles (06/2013 - 01/2003)|
|5.||Gildersleeve, Jeffrey C: 7 articles (01/2013 - 12/2005)|
|6.||Fujita-Yamaguchi, Yoko: 6 articles (02/2015 - 02/2009)|
|7.||Bay, Sylvie: 6 articles (06/2013 - 07/2004)|
|8.||Leclerc, Claude: 5 articles (10/2015 - 07/2004)|
|9.||Lo-Man, Richard: 5 articles (10/2015 - 07/2004)|
|10.||Osinaga, E: 5 articles (01/2014 - 03/2000)|
05/01/1992 - "The use of the S-Tn antigen as a tumor marker for various gynecologic cancers requires study."
09/22/2015 - "Elevated cell-surface expression of truncated carbohydrate structures such as Tn antigen (GalNAcα-Ser/Thr) is frequently observed during tumor progression. "
06/05/2015 - "A selective glycosylation strategy enabling access to all stereochemical combinations of tumor associated Thomsen-nouveau (Tn) antigen, D-GalNAc-O-Ser/Thr, has been developed. "
01/01/2015 - "While the Tn antigen cannot be detected in normal cells, Cosmc mutations inactivate T-synthase and consequently result in Tn antigen expression within certain cancers. "
01/01/2015 - "Tn antigen is a tumor associated glycan detected in 75-90 % of PDACs and up to 67 % in its precursor lesions. "
01/01/1995 - "T/Tn antigen vaccine is effective and safe in preventing recurrence of advanced breast carcinoma."
01/01/1994 - "T/Tn antigen vaccine is effective and safe in preventing recurrence of advanced human breast carcinoma."
08/01/2011 - "Here, we investigated the mechanism of action of a Tn antigen-specific chimeric mAb (Chi-Tn), which binds selectively to a wide variety of carcinomas, but not to normal tissues, in both humans and mice. "
01/01/2005 - "The lectin extracted from the seeds of Salvia sclarea (SSL) recognizes the Tn antigen (GalNAc alpha1-->Ser/Thr) expressed in certain human carcinomas. "
06/01/2001 - "O-glycosylation in Echinococcus granulosus: identification and characterization of the carcinoma-associated Tn antigen."
09/23/2010 - "To enable experimental approaches to study interactions of the Tn antigen with the immune system and analyze anti-Tn antibody responses in infection or disorders, we generated a Tn-expressing resource that can be used for high-throughput screening. "
10/01/2013 - "parvum that contain the Tn antigen induce immune responses upon infection. "
10/01/2013 - "These studies reveal that specific anti-glycopeptide antibodies that recognise the Tn antigen may be useful diagnostically and in defining the roles of parasite glycoconjugates in infections. "
08/01/2001 - "Utilising monoclonal antibodies anti-Tn antigen, anti-sialyl-Tn antigen and anti-T antigen, we have investigated the expression of the simple mucin-type carbohydrate antigens in 47 biopsy specimens of antral mucosa with chronic active gastritis, 25 of which had Helicobacter pylori infection. "
|4.||Breast Neoplasms (Breast Cancer)
02/01/2006 - "Study of the expression of Tn antigen in different types of human breast cancer cells using VVA-B4 lectin."
09/01/2005 - "Molecular basis of incomplete O-glycan synthesis in MCF-7 breast cancer cells: putative role of MUC6 in Tn antigen expression."
08/01/2005 - "We concluded that the lack of polymorphic MUC1 expression with Tn antigen is one characteristic related to aggressive breast cancer."
03/01/2014 - "We evaluated the AQD staining of Tn antigen on tissue microarrays consisting of 395 cores from 115 cases including three tumor cores and one normal-tissue core from each breast cancer case and three tumor cores from each benign case. "
07/01/2006 - "Because anti-Tn MAbs bound to Tn antigen clusters, we concluded that atypical MUC1 bearing the noncluster form of Tn antigen is implicated in aggressive growth of primary breast cancer cells, particularly in lymphatic metastasis."
04/01/1991 - "Despite its specificity, H17 does not react with TA3-Ha, a mouse mammary adenocarcinoma, known to express the Tn antigen (GalNAc alpha-O-Ser/Thr). "
07/01/1991 - "Tn antigen was observed throughout adenocarcinomas, squamous and small cell carcinomas in a relatively weak manner. "
06/01/1992 - "The antibody Tn5 (similar to BRIC111) was shown to be specific for human erythrocyte Tn antigen, whereas Tn56 reacted strongly with different glycoproteins carrying O-linked GalNAc alpha- residues, and was strongly bound to the murine adenocarcinoma cell line Ta3-Ha. "
01/01/1989 - "The expression of Lewisa blood group antigen and Tn antigen was detected in 76% and 62% of the pulmonary adenocarcinomas, respectively, but only one mesothelioma was stained for Lewisa antigen. "
01/01/1989 - "This study reveals that the majority of malignant mesotheliomas can be distinguished from pulmonary adenocarcinomas by immunohistochemcial staining for CEA, surfactant apoprotein, Lewisa antigen, and Tn antigen. "
|1.||Staphylococcal Protein A (A, Protein)
|2.||Immunoglobulin G (IgG)
|3.||desialylated ovine submaxillary mucin
|4.||keyhole-limpet hemocyanin (keyhole limpet hemocyanin)
|9.||Tumor Viral Antigens (Large T Antigen)
|3.||Quantum Dots (Quantum Dot)
|4.||Segmental Mastectomy (Lumpectomy)
|5.||Modified Radical Mastectomy (Mastectomy, Modified)