cloperastine

03/01/2012 - "Cloperastine-based cough syrup and acute dystonic reactions."
01/01/2011 - "Pharmacological and clinical overview of cloperastine in treatment of cough."
05/01/1988 - "[Cloperastine fendizoate in the treatment of cough-producing diseases in pediatrics]."
12/01/2022 - "Cloperastine is a pivotal antibechic widely prescribed to treat cough caused by respiratory diseases. "
01/01/2000 - "Acute dystonia in a young schizophrenic patient associated with ingestion of a cloperastine containing cough syrup."

01/01/2004 - "The efficacy of levocloperastine, a novel antitussive, which acts both centrally on the cough center and on peripheral receptors in the tracheobronchial tree in treating chronic cough, was compared with that of other standard antitussive agents (codeine, levodropropizine and DL-cloperastine) in six open clinical trials. "

05/01/2016 - "These results demonstrated that antitussive drugs (cloperastine, tipepidine and caramiphen) possessing inhibitory action on GIRK channels inhibit drug-induced hyperactivity in mice, suggesting that such antitussives may potentially be therapeutic for patients with ADHD. "

01/01/2023 - "In this study, we utilized an AlphaLISA-based high-throughput screening method adapted in our lab, and identified one FDA-approved drug, Candesartan cilexetil (Can, used in hypertension treatment) and one EMA-approved drug, Cloperastine hydrochloride (Clo, used in cough treatment) that had significant PRMT5-inhibitory activity, and their anti-tumor properties were validated using cancer phenotypic assays in vitro. "

01/01/2023 - "In this study, we utilized an AlphaLISA-based high-throughput screening method adapted in our lab, and identified one FDA-approved drug, Candesartan cilexetil (Can, used in hypertension treatment) and one EMA-approved drug, Cloperastine hydrochloride (Clo, used in cough treatment) that had significant PRMT5-inhibitory activity, and their anti-tumor properties were validated using cancer phenotypic assays in vitro. "