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leukotriene B5

Also Known As:

5,12-dihydroxy-6,8,10,14,17-eicosapentaenoic acid; LTB 5

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Almeida, Ewin B: 1 article (08/2019)
2.	Amaral, Jônatas B do: 1 article (08/2019)
3.	Bachi, André L L: 1 article (08/2019)
4.	Barros, Karina V: 1 article (08/2019)
5.	Jasiulionis, Miriam G: 1 article (08/2019)
6.	Oliveira, Luis V F: 1 article (08/2019)
7.	Paixão, Vitoria: 1 article (08/2019)
8.	Perez, Elizabeth C: 1 article (08/2019)
9.	Rossi, Marcelo: 1 article (08/2019)
10.	Silva, Karina P H: 1 article (08/2019)

Related Diseases

1.	Neoplasms (Cancer) 09/01/2009 - "Addition to the tumor inflammatory microenvironment of eicosapentaenoic acid, an omega3-polyunsaturated fatty acid with anti-inflammatory properties, or leukotriene B5, an eicosapentaenoic acid-derived leukotriene, significantly inhibited tumor development. " 08/01/2019 - "Although it has been previously demonstrated that acute inflammation can promote the tumor growth of a sub-tumorigenic dose of melanoma cells through of 5-lipoxygenase inflammatory pathway and its product leukotriene B4, and also that the peritumoral treatment with eicosapentaenoic acid and its product, leukotriene B5, reduces the tumor development, the effect of the treatment by gavage with omega-3 and omega-6 in the tumor microenvironment favorable to melanoma growth associated with acute inflammation has never been studied. "
2.	Psoriasis (Pustulosis Palmaris et Plantaris) 01/01/1989 - "A low-fat diet supplemented with dietary fish oil (Max-EPA) results in improvement of psoriasis and in formation of leukotriene B5."
3.	Melanoma (Melanoma, Malignant) 08/01/2019 - "Although it has been previously demonstrated that acute inflammation can promote the tumor growth of a sub-tumorigenic dose of melanoma cells through of 5-lipoxygenase inflammatory pathway and its product leukotriene B4, and also that the peritumoral treatment with eicosapentaenoic acid and its product, leukotriene B5, reduces the tumor development, the effect of the treatment by gavage with omega-3 and omega-6 in the tumor microenvironment favorable to melanoma growth associated with acute inflammation has never been studied. "
4.	Inflammation (Inflammations) 08/01/2019 - "Although it has been previously demonstrated that acute inflammation can promote the tumor growth of a sub-tumorigenic dose of melanoma cells through of 5-lipoxygenase inflammatory pathway and its product leukotriene B4, and also that the peritumoral treatment with eicosapentaenoic acid and its product, leukotriene B5, reduces the tumor development, the effect of the treatment by gavage with omega-3 and omega-6 in the tumor microenvironment favorable to melanoma growth associated with acute inflammation has never been studied. "
5.	Crohn Disease (Crohn's Disease) 11/01/1992 - "Ten patients with active Crohn's disease who have been managed with parenteral-nutrition therapy were administered a lipid emulsion either with [containing 0.6 g eicosapentaenoic acid (EPA)] or without fish oil for 2 wk. We isolated polymorphonuclear leukocytes (PMNLs) from the patients before and after this treatment and measured the amounts of leukotriene B4 (LTB4) and leukotriene B5 (LTB5) generated by activated PMNLs by reversed-phase HPLC. "

Related Drugs and Biologics

1.	Eicosapentaenoic Acid
2.	Leukotriene B4
3.	Fish Oils
4.	Leukotrienes
5.	Lipids
6.	Fatty Acids (Saturated Fatty Acids)
7.	Emulsions
8.	Arachidonate 5-Lipoxygenase (5 Lipoxygenase)
9.	Maxepa

Related Therapies and Procedures

1.	Fat-Restricted Diet (Diet, Fat Restricted)
2.	Therapeutics
3.	Parenteral Nutrition