peptidase 7
mouse gene pep-7 controlling this enzyme is associated with lymphoproliferative disease-inducer gene Arp
Networked: 4
relevant articles (0 outcomes,
0 trials/studies)
Bio-Agent Context: Research Results
Experts
| 1. | Busch, Michael:
1 article
(01/2021)
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| 2. | Downey-Kopyscinski, Sondra L:
1 article
(01/2021)
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| 3. | Esdar, Christina:
1 article
(01/2021)
|
| 4. | Friese-Hamim, Manja:
1 article
(01/2021)
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| 5. | Gaus, Stefanie:
1 article
(01/2021)
|
| 6. | Klein, Markus:
1 article
(01/2021)
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| 7. | Mitsiades, Constantine S:
1 article
(01/2021)
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| 8. | Musil, Djordje:
1 article
(01/2021)
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| 9. | Rohdich, Felix:
1 article
(01/2021)
|
| 10. | Sanderson, Michael P:
1 article
(01/2021)
|
Related Diseases
| 1. | Multiple Myeloma
01/01/2023
- " M3258 is an orally bioavailable, potent, selective, reversible inhibitor of the large multifunctional peptidase 7 (LMP7, β5i, PSMB8) proteolytic subunit of the immunoproteasome, a component of the cellular protein degradation machinery, highly expressed in malignant hematopoietic cells including multiple myeloma. " 01/01/2021
- " Large multifunctional peptidase 7 (LMP7/β5i/PSMB8) is a proteolytic subunit of the immunoproteasome, which is predominantly expressed in normal and malignant hematolymphoid cells, including multiple myeloma, and contributes to the degradation of ubiquitinated proteins. "
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| 2. | Carcinogenesis
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| 3. | Neoplasms (Cancer)
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| 4. | Hepatocellular Carcinoma (Hepatoma)
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