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ritipenem
carbapenem antibiotic; structure given in first source
Also Known As:
FCE 22101; FCE-22101; ritipenem sodium
Networked:
12
relevant articles (
3
outcomes,
2
trials/studies)
Relationship Network
Bio-Agent Context: Research Results
Organic Chemicals: 133
Amides: 2428
Lactams: 2198
beta-Lactams: 2386
Carbapenems: 4837
ritipenem: 12
Heterocyclic Compounds: 198
Fused-Ring Heterocyclic Compounds
2-Ring Heterocyclic Compounds
beta-Lactams: 2386
Carbapenems: 4837
ritipenem: 12
Related Diseases
1.
Respiratory Tract Infections (Respiratory Tract Infection)
03/01/1996 - "
[Comparative study on the efficacy of ritipenem acoxil and cefotiam hexetil in chronic lower respiratory tract infections by the double-blind method].
"
03/01/1989 - "
FCE 22101 and imipenem were very potent against the bacteria studied, including beta-lactamase producing strains, which can be isolated from patients with respiratory tract infections (MIC less than or equal to 8 mg/l).
"
03/01/1996 - "
To objectively evaluate the efficacy, safety and usefulness of the newly developed penem oral antibiotic, ritipenem acoxil (RIPM-AC), against chronic lower respiratory tract infections, we conducted a multi-center double-blind comparative study using cefotiam hexetil (CTM-HE) as a control drug.
"
2.
Intraabdominal Infections
03/01/1989 - "
FCE 22101 seems to be useful in the treatment of intra-abdominal infections and deserves further clinical investigation.
"
03/01/1989 - "
Efficacy of FCE 22101 compared with imipenem and with gentamicin plus metronidazole in the treatment of experimental intra-abdominal infections in rats.
"
03/01/1989 - "
This experimental model was used to compare the efficacies of FCE 22101, imipenem, and gentamicin combined with metronidazole in the treatment of intra-abdominal infections.
"
3.
Urinary Tract Infections (Urinary Tract Infection)
11/01/1995 - "
Dose finding study on the efficacy and safety of ritipenem in complicated urinary tract infections.
"
4.
Bacteriuria
03/01/1995 - "
Subanalyses of bacteriologic outcome showed that failure rates varied between 6% and 67% for ritipenem acoxil and between 1% and 43% for norfloxacin, depending on how significant posttherapy bacteriuria was defined; systematic studies are are clearly needed on how best to define significant posttherapy bacteriuria.
"
03/01/1995 - "
Five to 9 days after the completion of therapy, persistent bacteriuria was documented in more women given ritipenem acoxil than norfloxacin (95% confidence interval, 0.14; 0.38).
"
03/01/1995 - "
Interpretation of the bacteriologic outcome of antibiotic treatment for uncomplicated cystitis: impact of the definition of significant bacteriuria in a comparison of ritipenem acoxil with norfloxacin.
"
5.
Infections
03/01/1989 - "
Activity of FCE 22101 and other beta-lactam antibiotics against experimental genital infections in the rat and mouse.
"
05/01/1987 - "
On the basis of these results, FCE 22101 appears to be a promising antimicrobial agent for treatment of anaerobic infections, and further clinical investigations are indicated.
"
03/01/1989 - "
The therapeutic activities of the parenterally administered penem FCE 22101, cefuroxime and ampicillin were compared in an experimental model of genital infections in progesterone-treated virgin rats and normal female mice.
"
Related Drugs and Biologics
1.
Imipenem
2.
beta-Lactamases (beta-Lactamase)
3.
cefotiam hexetil
4.
Metronidazole (Metric)
5.
Gentamicins (Gentamicin)
6.
Norfloxacin
7.
Meropenem (Merrem)
8.
Anti-Bacterial Agents (Antibiotics)
9.
FCE 22891
10.
beta-Lactams
Related Therapies and Procedures
1.
Therapeutics