cirsiliol

01/31/2019 - "Based on these results, cirsiliol may be considered a promising compound against EMT in the therapeutic management of malignant melanoma."
01/31/2019 - "Cirsiliol Suppressed Epithelial to Mesenchymal Transition in B16F10 Malignant Melanoma Cells through Alteration of the PI3K/Akt/NF-κB Signaling Pathway."
01/31/2019 - "Cirsiliol was found to be effective in restraining the colony formation and migration of fibronectin-induced B16F10 metastatic melanoma cells. "
01/31/2019 - "In the present study, we investigated the potential of cirsiliol, a flavonoid isolated from Centaurea jacea L., in modulating the aggressive behavior of B16F10 metastatic melanoma cells, including EMT, and associated molecular mechanisms of action. "

10/07/2022 - "In this study, we first found that cirsiliol inhibited cell viability, colony formation, and wound healing abilities of HCT116 and SW480 colon cancer cells. "
10/07/2022 - "Cirsiliol targets STAT3 to inhibit colon cancer cell proliferation by regulating mitophagy."
10/07/2022 - "Cirsiliol regulates mitophagy in colon cancer cells via STAT3 signaling."
10/07/2022 - "The effects of cirsiliol in the tumorigenesis and progression of colon cancer remain unknown. "

10/07/2022 - "Cirsiliol is a natural product and has been found to exert anti-cancer effects in multiple tumors. "
03/17/2021 - "Cell proliferation, western blot and patient-derived xenograft tumor model were used to determine the inhibitory effects and mechanism of cirsiliol in ESCC. "
10/01/2019 - "Although cirsiliol is being used in cancer therapy, its pharmacological potential is limited by its low solubility and bioavailability. "
09/20/2013 - "In these mice, tumor volume was significantly reduced by combinational treatment with irradiation and rhamnetin or cirsiliol compared with irradiation alone. "
09/20/2013 - "Indeed, rhamnetin and cirsiliol increased the expression of tumor-suppressive microRNA, miR-34a, in a p53-dependent manner, leading to inhibition of Notch-1 expression. "

10/07/2022 - "The effects of cirsiliol in the tumorigenesis and progression of colon cancer remain unknown. "

07/31/2022 - "Cirsiliol mitigates Aβ fibrillation and underlying membrane-leakage associated neurotoxicity: A possible implication in the treatment of neurodegenerative disease."