adrenorphin

opioid octapeptide from human & bovine adrenal medulla & human phaeochromocytoma tumor; H-Tyr-Gly-Gly-Phe-Met-Arg-Arg-Val-NH2

Also Known As:

6,7-Arg-8-ValNH2-Met-enkephalin; Met-enkephalin, Arg(6,7)-ValNH2(8)-; enkephalin-Met, Arg(6,7)-ValNH2(8)-; enkephalin-Met, arginyl(6,7)-valinamide(8)-; methionine-enkephalin, Arg(6,7)-ValNH2(8)-; metorphamide; Adrenorphin

Networked: 8 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Nerve Tissue Proteins: 2
    - Neuropeptides: 6772
      - Opioid Peptides: 1339
        Enkephalins: 1042
        Methionine Enkephalin: 610
        adrenorphin: 8
- Peptides: 82426
  - Neuropeptides: 6772
    - Opioid Peptides: 1339
      - Enkephalins: 1042
        Methionine Enkephalin: 610
        adrenorphin: 8

Experts

1.	Abbruscato, Thomas J: 1 article (04/2014)
2.	Arumugam, Thiruma V: 1 article (04/2014)
3.	Karamyan, Vardan T: 1 article (04/2014)
4.	Rashid, Mamoon: 1 article (04/2014)
5.	Shah, Kaushik: 1 article (04/2014)
6.	Wangler, Naomi J: 1 article (04/2014)
7.	Yang, Li: 1 article (04/2014)

Related Diseases

1.	Pheochromocytoma 04/01/1987 - "Gel chromatographic studies revealed that immunoreactive adrenorphin consisted largely of material emerging at the position of synthetic adrenorphin in both pheochromocytoma and normal adrenal medulla tissue. " 04/01/1987 - "Studies on adrenorphin in pheochromocytoma." 04/01/1987 - "These results indicate the presence and secretion of adrenorphin in human pheochromocytomas. " 04/01/1987 - "Adrenomedullary pheochromocytomas contained a significantly larger amount of immunoreactive adrenorphin (2295 +/- 1092 pg/mg, mean +/- SE) than did extramedullary ones (17.8 +/- 8.4 pg/mg). " 04/01/1987 - "In 17 human pheochromocytomas from 11 patients, we found a remarkably wide distribution in immunoreactive adrenorphin levels (3-7771 pg/mg tissue). "
2.	Neoplasms (Cancer) 02/01/1985 - "Adrenorphin is the first C-terminally amidated form of opioid peptides isolated from human pheochromocytoma tumor and is considered to be generated out of proenkephalin A by unique processing. " 05/16/1984 - "Adrenorphin is the first C-terminally amidated form of opioid peptide isolated from human pheochromocytoma tumor and is considered to be generated out of proenkephalin A by unique processing. "
3.	Visceral Pain 01/01/1986 - "[Analgesic effect of metorphamide on skin pain and visceral pain]."
4.	Stroke (Strokes) 04/01/2014 - "Considering diversity of endogenous neurolysin substrates (neurotensin, bradykinin, angiotensins I/II, substance P, hemopressin, dynorphin A(1-8), metorphamide, somatostatin) and the well-documented role of these peptidergic systems in pathogenesis of stroke, resistance to ischemic injury and/or post-stroke brain recovery, our findings suggest that neurolysin may play a role in processes modulating the brain's response to stroke and its recovery after stroke."
5.	Respiratory Insufficiency (Respiratory Failure) 04/01/1985 - "Metorphamide (MET) elicited a potent, dose-dependent analgesia and respiratory depression in mice and rabbits. "

Related Drugs and Biologics

1.	Opioid Peptides (Opioid Peptide)
2.	proenkephalin
3.	Substance P
4.	Somatostatin (Somatotropin Release-Inhibiting Factor)
5.	Nicotine
6.	Neurotensin
7.	Methionine Enkephalin
8.	Catecholamines
9.	Bradykinin
10.	Angiotensins

Related Therapies and Procedures

1.	Analgesia