2,4-dihydroxypyridine

Also Known As:

4-hydroxy-2-pyridone

Networked: 2 relevant articles (1 outcomes, 0 trials/studies)

1.	Neoplasms (Cancer) 09/01/2023 - "Among them, arthpyrone O (3) not only exhibited potent efficacy against the proliferative activity of SCLC cells and induced apoptosis in vitro, but also significantly inhibited the growth of xenograft tumor based on SCLC cells in vivo, which indicated 4-hydroxy-2-pyridone alkaloids might been revised as privileged scaffolds in drug discovery." 01/01/2019 - "Apiosporamide, a 4-hydroxy-2-pyridone alkaloid from a deep-sea-derived fungus, Arthrinium sp. UJNMF0008, showed anti-proliferative effects toward a panel of human cancer cell lines, and the molecular mechanism in MG63 cells was then investigated in the current work. "
2.	Osteosarcoma (Osteogenic Sarcoma) 01/01/2019 - "Apiosporamide, A 4-hydroxy-2-pyridone Alkaloid, Induces Apoptosis Via PI3K/Akt Signaling Pathway In Osteosarcoma Cells."