|1.||Lang, Florian: 3 articles (01/2008 - 01/2003)|
|2.||Huber, Stephan M: 3 articles (01/2008 - 01/2003)|
|3.||Jackson, Terry: 2 articles (06/2010 - 01/2010)|
|4.||Monaghan, Paul: 2 articles (06/2010 - 01/2010)|
|5.||Pedersen, Stine Falsig: 2 articles (05/2009 - 01/2007)|
|6.||Lang, Karl S: 2 articles (11/2003 - 01/2003)|
|7.||Ishikawa, N: 2 articles (03/2001 - 02/2001)|
|8.||Ohashi, N: 2 articles (03/2001 - 02/2001)|
|9.||Hotta, Y: 2 articles (03/2001 - 02/2001)|
|10.||Matsui, K: 2 articles (03/2001 - 02/2001)|
08/01/1997 - "EIPA also limited the increase in Nai and [Ca]i during ischemia and improved Nai and [Ca]i recovery during reperfusion (P<0.05). "
11/01/1994 - "Thus, under our conditions the Na+/H+ antiporter did not play a critical role in the maintenance of intracellular pH. EIPA treatment resulted in improved recovery (P < 0.005) of mechanical function after 20 min of ischemia. "
09/01/1998 - "The aim of the present study was to determine to what extent preischemic treatment with EIPA could reduce infarct size in an in situ rabbit model of regional ischemia and reperfusion. "
02/01/2001 - "The recovery rate of LVDP from ischemia (40 min) by reperfusion was 36.8% in the control experiments, whereas in the presence of SM 10(-7) M, a gradual increase to 75.9% (55.5% with 10(-8) M), in contrast to EIPA (10(-7) M), 47.5% was observed. "
08/21/1999 - "The increase in locomotor activity in the EIPA-treated group was significantly less than that of the control group at both 24 h and 6-day post-ischemia. "
07/01/2005 - "However, EIPA (20 microM) blocked most of the stimulation caused by acidosis when applied to the lumen but not interstitium, demonstrating that induction of brush-border NHE activity is important. "
01/01/2003 - "Recovery from the bafilomycin-induced acidosis at pHo 6.5-7.4 was prevented by EIPA. "
06/01/2002 - "Additionally, the inhibitory potency of the most active compounds was assessed by measuring the inhibition of the EIPA-sensitive (22)Na(+) uptake (UIA) by human platelets after intracellular acidosis. "
01/01/1999 - "SM-15681 (10(-8)-10(-7) M) inhibited pH recovery of acidosis in the rat myocardium in a concentration-dependent manner and the IC50 value of SM-15681 (80 nM) was similar to that of EIPA. "
08/01/1998 - "Thus, the activity of Na+/H+ exchanger during ischemic acidosis, assessed as the increase of DeltaH+ induced by addition of EIPA to bicarbonate buffer, was higher in non-DM (0.52) than DM (0.17). "
06/01/2006 - "The treatment of cancer cells with bafilomycine A1 or EIPA individually slightly lowered pHi of the cells in vitro and increased the thermosensitivity of the cells. "
06/01/1993 - "The fact that lowering the pHi and increasing thermal sensitivity of tumor cells by EIPA are more pronounced in acidic medium suggests that the acidic intratumor environment may be exploited to selectively increase the thermal damage in tumors relative to normal tissues by EIPA or its analogs."
02/01/2011 - "EIPA also inhibited tumor growth in nude mouse xenografts of HCC cells. "
10/11/1996 - "When EIPA was injected at a dose of 10 micrograms/g body weight, it was cleared rapidly from liver, but concentrations > 1 microM were sustained for at least 2 h in murine kidney and in a transplantable tumor."
04/01/2010 - "EIPA treatment reduced cathepsin B secretion and HGF-induced invasion by the tumor cells. "
09/01/1991 - "These results suggest that EIPA prevents ventricular arrhythmias, contracture and myocardial cellular injury during reperfusion after 15 min of ischemia by inhibiting Na+/H+ exchange, while amiloride exerts more powerful protection against these events than EIPA during reperfusion after 30 min of ischemia by inhibiting both Na+/H+ and Na+/Ca2+ exchange."
01/01/1996 - "Concentration-dependent protective effects against veratrine-contractures, in the absence of negative inotropic responses, were observed with HOE 694 (IC50 = 20.1(7.6-27.0) microM, n = 24) and with the chemically related amiloride derivatives DMA, EIPA, HMA and MIA, but not with amiloride itself. "
06/01/1993 - "In the present study, the efficacy of 5-(N-ethyl-N-isopropyl) amiloride (EIPA), an analog of amiloride, to lower the pHi and sensitize tumor cells to hyperthermia was investigated. "
03/01/2005 - "Hyperthermia at 42 degrees C caused only a 15-20% increase in Nai+. In the presence of 3 microM 5-(N-ethyl-N-isopropyl)amiloride (EIPA), an inhibitor of the Na+/H+ exchanger, the increase in Nai+ during 45 degrees C hyperthermia was attenuated, suggesting that the heat-induced increase in Nai+ was mainly due to an increase in Na+/H+ anti-porter activity. "
|9.||4,4'- Diisothiocyanostilbene- 2,2'- Disulfonic Acid (DIDS)
|10.||Adenosine Triphosphate (ATP)
|2.||Heterologous Transplantation (Xenotransplantation)
|5.||Infusion Pumps (Infusion Pump)