H 142

decapeptide inhibitor of human renin; RN given refers to all L-isomer

Also Known As:

H-142; L-Lysine, N2-(N-(N-(N-(4-methyl-2-((N-(N-(1-(N-L-prolyl-L-histidyl)-L-prolyl)-L-phenylalanyl)-L-histidyl)amino)pentyl)-L-valyl)-L-isoleucyl)-L-histidyl)-, (S)-

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Serpins: 906
    - Angiotensinogen: 1828
      - H 142: 3
  - Protein Precursors: 37
    - Angiotensinogen: 1828
      - H 142: 3
- Peptides: 82426
  - Serpins: 906
    - Angiotensinogen: 1828
      - H 142: 3
  - Oligopeptides: 519
    - Angiotensins: 6068
      - Angiotensinogen: 1828
        H 142: 3

Experts

1.	Dvořáček, Jan: 1 article (01/2022)
2.	Dvořáčková, Helena: 1 article (01/2022)
3.	Hueso González, Paloma: 1 article (01/2022)
4.	Vlček, Vítězslav: 1 article (01/2022)
5.	Bonneville, F: 1 article (08/2013)
6.	Guidolin, B: 1 article (08/2013)
7.	Larrue, V: 1 article (08/2013)
8.	Nasr, N: 1 article (08/2013)
9.	Ssi-Yan-Kai, G: 1 article (08/2013)

Related Diseases

1.	Stroke (Strokes) 08/01/2013 - "Of 159 patients with a TIA or minor stroke within the last 24 h, 142 had a readable acoustic temporal bone window (89.3%). "
2.	Cutaneous Leishmaniasis 04/01/1993 - "Ten 2-substituted quinoline alkaloids isolated from a plant used for treatment of New World cutaneous leishmaniasis have antileishmanial in vitro activities against the extracellular forms of Leishmania spp. BALB/c mice infected with Leishmania amazonensis PH8 or H-142 or Leishmania venezuelensis were treated 1 day after the parasitic infection with a quinoline alkaloid (100 mg/kg of body weight per day) or with reference drug N-methylglucamine antimonate (Glucantime) (56 mg of pentavalent antimony [Sbv] per kg per day) for 14 days. "
3.	Parasitic Diseases (Parasitic Disease) 04/01/1993 - "Ten 2-substituted quinoline alkaloids isolated from a plant used for treatment of New World cutaneous leishmaniasis have antileishmanial in vitro activities against the extracellular forms of Leishmania spp. BALB/c mice infected with Leishmania amazonensis PH8 or H-142 or Leishmania venezuelensis were treated 1 day after the parasitic infection with a quinoline alkaloid (100 mg/kg of body weight per day) or with reference drug N-methylglucamine antimonate (Glucantime) (56 mg of pentavalent antimony [Sbv] per kg per day) for 14 days. "
4.	Burns 01/01/2022 - "While in the case of the control variant (Natural conditions, N) the buffering capacity of the soil was measured at 144.93 ± 0.25, the addition of different amendments decreased the buffering capacity in the following order: Bare soil (B) 142.73±0.21 > TerraCotem hydroaborbent polymer (H) 142.23±.15 > Pine mulch (P) 140.40±0.30, Prescribed burn (F) 138.20±0.30, Sludge (S) 127.47±0.15. "
5.	Body Weight (Weight, Body) 04/01/1993 - "Ten 2-substituted quinoline alkaloids isolated from a plant used for treatment of New World cutaneous leishmaniasis have antileishmanial in vitro activities against the extracellular forms of Leishmania spp. BALB/c mice infected with Leishmania amazonensis PH8 or H-142 or Leishmania venezuelensis were treated 1 day after the parasitic infection with a quinoline alkaloid (100 mg/kg of body weight per day) or with reference drug N-methylglucamine antimonate (Glucantime) (56 mg of pentavalent antimony [Sbv] per kg per day) for 14 days. "

Related Drugs and Biologics

1.	Polymers
2.	Antimony
3.	Alkaloids
4.	Meglumine Antimoniate
5.	quinoline