|1.||Paini, Alicia: 1 article (04/2014)|
|2.||Boonpawa, Rungnapa: 1 article (04/2014)|
|3.||van Bladeren, Peter J: 1 article (04/2014)|
|4.||Martati, Erryana: 1 article (04/2014)|
|5.||Punt, Ans: 1 article (04/2014)|
|6.||van den Berg, Johannes H J: 1 article (04/2014)|
|7.||Rietjens, Ivonne M C M: 1 article (04/2014)|
|8.||Spenkelink, Albertus: 1 article (04/2014)|
|9.||Vervoort, Jacques: 1 article (04/2014)|
04/01/1987 - "Concurrent administration of the hepatic sulfotransferase inhibitor pentachlorophenol with HOS in each of the above assays almost completely inhibited the initiating and promoting activities of HOS for the formation of enzyme-altered foci and tumors; these data strongly suggest that both the initiating and promoting activities are mediated by the sulfuric acid ester, 1'-sulfooxysafrole. "
04/01/2014 - "Safrole, present in mace and its essential oils, causes liver tumors in rodents at high dose levels due to formation of a DNA reactive 1'-sulfooxysafrole. "
|2.||Body Weight (Weight, Body)
04/01/2014 - "Dosing safrole at 50mg/kg body weight and malabaricone C-containing mace extract at a ratio reflecting the relative presence in mace, and assuming 100% or 1% uptake of malabaricone C-containing mace extract, the model predicted inhibition of 1'-sulfooxysafrole formation for rats and humans by 90% and 100% or 61% and 91%, respectively. "
|1.||A-Form DNA (A-DNA)
|3.||Pentachlorophenol (Sodium Pentachlorophenate)
|4.||Volatile Oils (Essential Oils)