lactosaminoglycan

cell surface glycoconjugate of embryonal carcinoma cells; core structure composed of repeating N-acetyllactosamine (Gal-GlcNAc) disaccharides; branched lactosaminoglycan from Band 3 gloycoprotein of adult human erythrocytes

Also Known As:

Networked: 12 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Related Diseases

1.	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 10/25/1985 - "These results indicate that chronic myelogenous leukemia cells express unique polylactosaminoglycan structures which are distinct from normal mature granulocytes." 06/25/1988 - "The biochemical properties and amino acid sequence of mLAMP-1 were highly similar to those of two other molecules that have been studied as cell surface onco-differentiation antigens: a highly sialylated polylactosaminoglycan-containing glycoprotein isolated from human chronic myelogenous leukemia cells (Viitala, J., Carlsson, S. "
2.	Congenital Dyserythropoietic Anemia (Dyserythropoietic Anemia, Congenital) 01/01/1984 - "The results indicate that anomalies in glycosylation occurred specifically in lactosaminoglycan glycoproteins of HEMPAS erythrocytes." 05/25/1987 - "Primary defect of congenital dyserythropoietic anemia type II. Failure in glycosylation of erythrocyte lactosaminoglycan proteins caused by lowered N-acetylglucosaminyltransferase II."
3.	Embryonal Carcinoma 10/01/1983 - "Embryonal carcinoma (EC) cells possess a complex cell surface glycoconjugate called lactosaminoglycan, whose core structure is composed of repeating N-acetyllactosamine (Gal leads to GlcNAc) disaccharides. "
4.	Colorectal Neoplasms (Colorectal Cancer) 06/15/1992 - "However, the lactosaminoglycan sequences are highly branched, unlike those associated with colorectal tumor cells."
5.	Virus Diseases (Viral Diseases) 03/01/1988 - "Investigation of the polypeptides produced by influenza B/Lee/40 virus infection of several cell types and another strain of influenza B virus suggested that the signal for modification to polylactosaminoglycan is contained in NB. "

Related Drugs and Biologics

1.	Glycoproteins (Glycoprotein)
2.	Glycoconjugates
3.	N-acetyllactosamine
4.	Galectins (Galectin)
5.	Lectins
6.	Sulfotransferases
7.	Proteins (Proteins, Gene)
8.	Peptides (Polypeptides)
9.	Keratan Sulfate
10.	Disaccharides