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fenprostalene
RN given refers to (1R*,2R*,3R*,5S*)-(E)-(3R*)-isomer; structure given in first source
Also Known As:
Synchrocept B; methyl 7-(3,5-dihydroxy-2-(3-hydroxy-4-phenoxy-1-butenyl)cyclopentyl)-4,5-heptadienoate
Networked:
8
relevant articles (
3
outcomes,
3
trials/studies)
Relationship Network
Bio-Agent Context: Research Results
Lipids: 114793
Fatty Acids: 27405
Unsaturated Fatty Acids: 8236
Eicosanoids: 3262
Prostaglandins: 17100
Synthetic Prostaglandins: 823
Synthetic Prostaglandins F: 2
fenprostalene: 8
Biological Factors: 2472
Inflammation Mediators: 1113
Synthetic Prostaglandins: 823
Synthetic Prostaglandins F: 2
fenprostalene: 8
Autacoids: 276
Eicosanoids: 3262
Prostaglandins: 17100
Synthetic Prostaglandins: 823
Synthetic Prostaglandins F: 2
fenprostalene: 8
Related Diseases
1.
Retained Placenta
02/01/1996 - "
In this study, 90% of animals treated with fenprostalene calved within a 20-h period, but with a high incidence of retained placenta.
"
09/01/1987 - "
The longer biological half-life for fenprostalene than for prostaglandin F(2alpha) provided no improvement in increasing synchrony of parturition or decreasing frequency of retained placenta.
"
02/01/1996 - "
Estradiol-17 beta benzoate did not reduce incidence of retained placenta in animals treated with fenprostalene (group B vs. group D) but tended to reduce incidence in uninduced animals (group A vs. group C).
"
02/01/1996 - "
Effects of fenprostalene and estradiol-17 beta benzoate on parturition and retained placenta in dairy cows and heifers.
"
09/01/1987 - "
The incidence of placenta retained for >24 h was higher for induced than spontaneous parturition (21.0 vs 0.0%), but it did not differ (P >0.1) between cows treated with prostaglandin F(2alpha) or fenprostalene (19.2 vs 22.6%).
"
2.
Cysts
11/01/1983 - "
was concluded that, if correctly diagnosed, luteal cysts can be successfully treated with fenprostalene, and conception rates following treatment can be expected to be normal.
"
11/01/1983 - "
Treatment with fenprostalene was very effective for luteal cysts: a high percentage of treated cows exhibited estrus within seven days after treatment.
"
11/01/1983 - "
Sixty-two dairy cows diagnosed as having cystic ovarian degeneration were used to study the correlation between rectal palpation findings and plasma progesterone concentrations and the response of cysts to treatment using fenprostalene, a luteolytic agent.
"
3.
Follicular Cyst (Follicular Cysts)
04/01/1993 - "
It was concluded that the administration of fenprostalene following fertirelin treatment is effective in shortening the interval from treatment to conception in cows with follicular cysts.
"
11/01/1983 - "
However, cows diagnosed as having follicular cysts, but with progesterone concentrations of 1 ng/mL or more, responded better to fenprostalene treatment than cows with low progesterone concentrations.It
"
04/01/1993 - "
Effect of fenprostalene 14 days after fertirelin treatment on intervals from treatment to conception in cows with follicular cysts diagnosed by milk progesterone test.
"
4.
Dystocia
09/01/1997 - "
Postpartum plasma PGF metabolite profile in cows with dystocia and/or retained placenta, and effect of fenprostalene on uterine involution and reproductive performance.
"
09/01/1997 - "
Objectives of this study were to show postpartum plasma PGF2 alpha metabolite (PGFM) profile, to clarify whether endogenous PGF2 alpha plays a certain role in the uterine involution in cows with dystocia and/or retained placenta, and to examine the effects of fenprostalene, a long-acting PGF2 alpha analog, on the uterine involution and reproductive performance of the cows with abnormal puerperium.
"
5.
Pyometra
12/15/1995 - "
Treatment with oxytetracycline and fenprostalene (group 2) increased (P < 0.05) the frequency of pyometra.
"
Related Drugs and Biologics
1.
Prostaglandins
2.
fertirelin
3.
Progesterone
4.
Dinoprost
5.
Luteolytic Agents
6.
15-keto-13,14-dihydroprostaglandin F2alpha (PGFM)
7.
Polyethylene (Polythene)
8.
Prostaglandins F
9.
Oxytetracycline (Terramycin)
10.
estradiol-17 beta-benzoate
Related Therapies and Procedures
1.
Aftercare (After-Treatment)