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UDPgalactose-glucosylceramide galactosyltransferase

Also Known As:

GL2 synthase; lactosylceramide synthase

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Transferases: 6589
    - Glycosyltransferases: 784
      - Hexosyltransferases
        Galactosyltransferases: 243
        UDPgalactose-glucosylceramide galactosyltransferase: 3

Experts

1.	Bandaru, Veera Venkata Ratnam: 2 articles (01/2019 - 01/2013)
2.	Hou, Jennifer: 2 articles (01/2019 - 01/2013)
3.	Chatterjee, Subroto B: 1 article (01/2019)
4.	Pezhouh, Maryam Kherad: 1 article (01/2019)
5.	Sharma, Rajni: 1 article (01/2019)
6.	Syed Rifat Mannan, Abul Ala: 1 article (01/2019)
7.	Alsaeedi, Nezar: 1 article (01/2013)
8.	Chatterjee, Subroto: 1 article (01/2013)
9.	Halushka, Marc K: 1 article (01/2013)
10.	Haughey, Norman J: 1 article (01/2013)

Related Diseases

1.	Colorectal Neoplasms (Colorectal Cancer) 01/01/2019 - "Lactosylceramide synthase β-1,4-GalT-V: A novel target for the diagnosis and therapy of human colorectal cancer."
2.	Respiratory Hypersensitivity 07/01/2010 - "In previously OVA-sensitized mice, intra-nasal administration of ASOs to GCS, GM3S or lactosylceramide synthase (LCS) significantly suppressed metacholine-induced airway hyperresponsiveness and pulmonary inflammation to a subsequent local challenge with OVA. "
3.	Pneumonia (Pneumonitis) 07/01/2010 - "In previously OVA-sensitized mice, intra-nasal administration of ASOs to GCS, GM3S or lactosylceramide synthase (LCS) significantly suppressed metacholine-induced airway hyperresponsiveness and pulmonary inflammation to a subsequent local challenge with OVA. "
4.	Neoplasms (Cancer) 01/01/2013 - "Mice fed D- threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol (D-PDMP), an inhibitor of glucosylceramide synthase and lactosylceramide synthase (LCS: β-1,4-GalT-V), showed marked reduction in tumor volume. "

Related Drugs and Biologics

1.	RV 538 (PDMP)
2.	ceramide glucosyltransferase

Related Therapies and Procedures

1.	Therapeutics
2.	Intranasal Administration