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tyrosinol

amino alcohol analog of tyrosine; RN given refers to parent cpd(S)-isomer

Also Known As:

tyrosinol hydrochlirde, (R)-isomer

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Amino Acids: 30675
  - Cyclic Amino Acids: 3
    - Aromatic Amino Acids: 467
      - Tyrosine: 10509
        tyrosinol: 3

Experts

1.	Bai, Li-Yuan: 1 article (06/2011)
2.	Byrd, John C: 1 article (06/2011)
3.	Chen, Ching-Shih: 1 article (06/2011)
4.	Chiu, Chang-Fang: 1 article (06/2011)
5.	Frissora, Frank: 1 article (06/2011)
6.	Jarjoura, David: 1 article (06/2011)
7.	Kulp, Samuel K: 1 article (06/2011)
8.	Ma, Yihui: 1 article (06/2011)
9.	Mani, Rajeswaran: 1 article (06/2011)
10.	Mo, Xiaokui: 1 article (06/2011)

Related Diseases

1.	Experimental Melanoma 05/14/1993 - "B16 melanoma cells were incubated for different time intervals in the presence of D- or L-phenylalaninol (PHE), D- or L-alaninol (AL), D- or L-leucinol (LE), L-histidinol (HIS), L-tyrosinol (TYR) and L-methioninol (MET). "
2.	Burkitt Lymphoma (Burkitt's Lymphoma) 06/01/2011 - "Herein we demonstrate that OSU-DY7, a novel D-tyrosinol derivative targeting p38 mitogen-activated protein kinase (MAPK), mediates cytotoxicity in lymphocytic cell lines representing CLL (MEC-1), acute lymphoblastic leukaemia (697 cells), Burkitt lymphoma (Raji and Ramos) and primary B cells from CLL patients in a dose- and time-dependent manner. " 06/01/2011 - "OSU-DY7, a novel D-tyrosinol derivative, mediates cytotoxicity in chronic lymphocytic leukaemia and Burkitt lymphoma through p38 mitogen-activated protein kinase pathway."
3.	Breast Neoplasms (Breast Cancer) 12/15/2010 - "Interestingly, the D- and L-tyrosinol-chlorambucil derivatives with 10 carbon atoms spacer are selective towards MCF-7 (ER+) breast cancer cell line."

Related Drugs and Biologics

1.	p38 Mitogen-Activated Protein Kinases
2.	Histidinol
3.	Chlorambucil (Leukeran)
4.	Carbon
5.	leucinol
6.	2-aminopropanol
7.	methioninol
8.	phenylalaninol