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1,4-dioxin

Also Known As:

p-dioxin

Networked: 11 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Dioxins and Dioxin-like Compounds: 5
  - Dioxins: 1199
    - 1,4-dioxin: 11
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Dioxins: 1199
    - 1,4-dioxin: 11

Experts

1.	Chen, Qiang: 1 article (10/2020)
2.	Ding, Xionghui: 1 article (10/2020)
3.	Lei, Junqiu: 1 article (10/2020)
4.	Qiu, Lin: 1 article (10/2020)
5.	Chen, Yao: 1 article (01/2020)
6.	Cui, Lingling: 1 article (01/2020)
7.	Gao, Zhan: 1 article (01/2020)
8.	He, Zhidong: 1 article (01/2020)
9.	Ji, Mengmeng: 1 article (01/2020)
10.	Li, Ning: 1 article (01/2020)

Related Diseases

1.	Cleft Palate (Palate, Cleft) 10/15/2020 - "2,3,7,8-Tetrachlorodibenzo- p-dioxin (TCDD) effectively induces cleft palate at increased doses, but its mechanism of involvement is unclear, and arguments have examined palatal shelf contact and/or fusion failure. " 01/01/2020 - "Oct4 plays a role in 2, 3, 7, 8 - tetrachlorobenzo-p-dioxin (TCDD) inducing cleft palate and inhibiting mesenchymal proliferation." 05/09/2019 - "Objective: To investigate the expression of gamma-aminobutyric acid type A receptor beta3 subunit (GABRB3) on cleft palate in C57BL/6J mice induced by 2,3,7,8-tetrachlorodibenzo- p-dioxin (TCDD). " 01/01/2020 - "The 2,3,7,8-tetrachlorodibenzo- p-dioxin (TCDD) is a well-known environmental teratogenic agent for cleft palate and Aryl hydrocarbon receptor (AhR) pathway can be activated by dioxins. "
2.	Breast Neoplasms (Breast Cancer) 02/01/2008 - "Here, we analyze the interference between the AhR signaling, activated by 10 nM 2,3,7,8-tetrachlorodibenzo- p-dioxin (TCDD), and the HIF-1 alpha pathway, induced by hypoxia (5% O2), in two human cell lines, the breast carcinoma cell line MCF-7 and the hepatocyte cell line HepG2. " 07/01/2008 - "The primary purpose of this research is to investigate the effects of 2,3,7,8-tetrachlorodibenzo- p-dioxin (TCDD) pretreatment and estrogen receptors-alpha (ER alpha) status on the induction of DNA damage by 17beta-estradiol (E 2) in human ER alpha(+)/MCF-7 and ER alpha(-)/MDA-MB-231 breast cancer cells. " 09/01/2010 - "In estrogen receptor- alpha (ER alpha )-positive and BRCA-1 wild-type MCF-7 breast cancer cells, we investigated the influence of AhR activation with the agonist 2,3,7,8 tetrachlorobenzo(p)dioxin (TCDD) on epigenetic regulation of the BRCA-1 gene and the preventative effects of Res. We report that activation and recruitment of the AhR to the BRCA-1 promoter hampers 17 beta -estradiol (E2)-dependent stimulation of BRCA-1 transcription and protein levels. "
3.	Chloracne 11/19/2018 - "2,3,7,8-Tetrachlordibenzo- p-dioxin (TCDD) is an environmental pollutant that can cause various toxic effects, including chloracne, metabolic syndrome, and immune suppression. "
4.	Metabolic Syndrome (Dysmetabolic Syndrome X) 11/19/2018 - "2,3,7,8-Tetrachlordibenzo- p-dioxin (TCDD) is an environmental pollutant that can cause various toxic effects, including chloracne, metabolic syndrome, and immune suppression. "
5.	Porphyria Cutanea Tarda 02/01/2008 - "The dysfunction of hepatic heme synthesis by 2,3,7,8-tetrachlordibenzo- p-dioxin (TCDD) in mice, enhanced by iron, leads to accumulation of uroporphyrins I and III (uroporphyria) and resembles the human disorder porphyria cutanea tarda (PCT) precipitated by alcohol and estrogenic drugs. "

Related Drugs and Biologics

1.	Polychlorinated Dibenzodioxins (TCDD)
2.	Estrogen Receptor alpha
3.	tert-Butylhydroperoxide
4.	Aryl Hydrocarbon Receptors (Aryl Hydrocarbon Receptor)
5.	Transforming Growth Factor beta (TGF-beta)
6.	Uroporphyrins
7.	Thioacetamide (Thioacetamid)
8.	Streptozocin (Streptozotocin)
9.	Proteins (Proteins, Gene)
10.	Methotrexate (Mexate)